ENGLISH

Notch Regulation of the Immune System

By Anna Bigas , Teresa D’Altri , Lluis Espinosa (auth.) , Freddy Radtke (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2012
ISBN
978-3-642-24293-9, 978-3-642-24294-6
DOI
10.1007/978-3-642-24294-6
Language
english
Format
PDF
Filesize
3 MB (2814728 bytes)
Series
Current Topics in Microbiology and Immunology 360
Edition
1
Pages
184\191
Time added
2014-06-12 06:00:00
Immunology

Description

Notch signaling regulates many cell fate decision and differentiation processes during embryonic development and tissue homeostasis. Moreover, disregulation of the pathway is associated with human disorders and cancer. In the last 15 years it became evident that Notch plays important roles in the hematopoietic system as well as in the regulation of immune responses. This special issue on Notch regulation of the immune system summarizes recent advances and covers multiple aspects of Notch signaling within the hematopoietic and the immune system. This issue covers subjects including Notch function in embryonic and adult hematopoietic stem cells, lymphocyte development and function as well as in T cell leukemia.

Similar books