ENGLISH

G protein-coupled receptors in drug discovery

By Richard M. Eglen , Terry Reisine (auth.) , Wayne R. Leifert (eds.)

Book information

Publisher
Humana Press
Year
2009
ISBN
9781603273169, 1603273166, 9781603273176, 1603273174
DOI
10.1007/978-1-60327-317-6
Open Library ID
OL24815180M
Language
english
Format
PDF
Filesize
8 MB (8334742 bytes)
Series
Methods in Molecular Biology 552
Edition
1
Pages
376\369
Library
Kingdwarf
Time added
2010-01-07 06:59:20
Pharmacology/Toxicology

Description

The G protein-coupled receptors (GPCRs), known to be one of the largest superfamilies in the human genome, underpin a multitude of physiological processes and represent a significant target for bioactive and drug discovery programs. In G Protein-Coupled Receptors in Drug Discovery: Methods and Protocols, experts in the field provide a range of classic and cutting-edge laboratory protocols developed for GPCR research, as well as several current review articles relevant to the area of high throughput GPCR screening, with discussion on GPCR structure and GPCR signalling. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, G Protein-Coupled Receptors in Drug Discovery: Methods and Protocols serves to aid all those who wish to further the vital research in their GPCR drug discovery programs.

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