ENGLISH

Bacterial Therapy of Cancer: Methods and Protocols

By Robert M. Hoffman

Book information

Publisher
Humana Press
Year
2016
ISBN
1493935135, 9781493935130
DOI
10.1007/978-1-4939-3515-4
ISSN
1064-3745
LCC
2015960794
Language
english
Format
PDF
Filesize
7 MB (7407247 bytes)
Series
Methods in Molecular Biology 1409
Pages
xvi+186\203
Topic
Biology Molecular
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2016-02-05 20:41:10
Cancer Research

Description

This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.

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