ENGLISH

Cancer Genetics

By Kenneth Offit , Peter Thom (auth.) , Boris Pasche (eds.)

Book information

Publisher
Springer US
Year
2010
ISBN
1441960325, 9781441960320, 9781441960337
DOI
10.1007/978-1-4419-6033-7
Language
english
Format
PDF
Filesize
2 MB (1827602 bytes)
Series
Cancer Treatment and Research 155
Edition
1
Pages
112\123
Topic
Medicine Oncology
Orientation
no
Scanned
no
Time added
2011-06-04 13:46:07
Oncology; Cancer Research; Human Genetics

Description

Cancer genetics has revolutionized the practice of medicine as inherited genetic information helps predicts which individuals are at risk of developing various forms of cancer. Furthermore, somatically acquired genetic changes help identify therapeutic targets for patients with several common tumor types such as breast and colon cancer. Cancer Genetics reviews seminal discoveries such as genetic susceptibility to gastric cancer, ethical issues related to cancer genetics, the role of common variants in the development of breast cancer, novel genetic findings related to neuroblastoma, and the role of constitutively decreased TGF-beta signaling, which is emerging as one of the most common causes of colorectal cancer. The book has been written for all clinicians and researchers interested in cancer genetics, including oncologists, genetic counselors and cancer researchers both in academia and in industry. "Genetic alterations are a fundamental component of all cancers. This text highlights critical issues relevant for both basic scientists and clinicians. Recognized thought leaders in the field discuss current knowledge and future challenges." - Steven T. Rosen, M.D., Series Editor

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2010 · PDF