Cancer Genetics and Therapeutics: Focus on Phytochemicals

Description

The book discusses cancer and the potential use of phytochemicals as cancer therapeutics. It begins with the basics of cancer, including the definition, types, etiology and molecular mechanisms involved, before discussing the fundamentals of diagnosis, treatment and associated problems as well as remedial measures. Since cancer is not a single disease, and the mechanisms of carcinogenesis are different for different cancers, it examines the genes and proteins involved in carcinogenesis, and signal transduction pathways for each individual cancer type. Further, the book reviews the latest research on phytochemicals for cancer treatment, highlighting their anti-cancer properties, sources, structure, active biomolecules and probable mechanisms of action, and describing their biochemical properties in the context of cancer prevention and treatment. Front Matter ....Pages i-xvi Cancer: Types and Hallmarks (Madhumita Roy, Amitava Datta)....Pages 1-26 Cancer: Genetics and Important Pathways (Madhumita Roy, Amitava Datta)....Pages 27-48 Fundamentals of Phytochemicals (Madhumita Roy, Amitava Datta)....Pages 49-81 Drugs and Phytochemicals (Madhumita Roy, Amitava Datta)....Pages 83-109 Molecular Mechanisms of Phytochemical Actions in Cancer (Madhumita Roy, Amitava Datta)....Pages 111-138 Improvement of Cancer Therapy Using Phytochemicals (Madhumita Roy, Amitava Datta)....Pages 139-164 Pharmacogenomics and Phytochemicals (Madhumita Roy, Amitava Datta)....Pages 165-186 Phytochemicals as Bioenhancers (Madhumita Roy, Amitava Datta)....Pages 187-205 Back Matter ....Pages 207-227