ENGLISH

Acute Myelogenous Leukemia

By Farhad Ravandi , Francis Giles (auth.) , Judith E. Karp MD (eds.)

Book information

Publisher
Humana Press
Year
2007
ISBN
978-1-58829-621-4, 978-1-59745-322-6
DOI
10.1007/978-1-59745-322-6
Language
english
Format
PDF
Filesize
43 MB (45260257 bytes)
Series
Contemporary Hematology
Edition
1
Pages
426\432
Orientation
yes
Scanned
yes
Time added
2013-10-21 08:10:53
Hematology; Oncology; Cancer Research; Internal Me

Description

Acute Myelogenous Leukemia is a timely compilation of new concepts in the molecular pathogenesis and molecular therapy of acute myelogenous leukemia (AML). The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation. There is an emphasis throughout on the bidirectional flow of knowledge between the clinical and laboratory arenas, and both basic and clinical scientists will benefit from this translational text.

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