ENGLISH

Metabolic Turnover in the Nervous System

By Robert L. Herrmann , A. Lajtha , Adil E. Shamoo , N. Marks , J. R. Smythies , D. A. Rappoport , R. R. Fritz , S. Yamagami , A. V. Palladin , N. M. Poljakova , Isaac Schenkein , Louis Sokoloff , William A. Brodsky , Irving L. Schwartz , H. R. Wyssbrod , W. N. Scott , W. A. Brodsky , I. L. Schwartz (auth.)

Book information

Publisher
Springer US
Year
1971
ISBN
978-1-4615-7171-1, 978-1-4615-7169-8
DOI
10.1007/978-1-4615-7169-8
Language
english
Format
PDF
Filesize
12 MB (12153085 bytes)
Edition
1
Pages
424\412
Time added
2014-01-18 08:00:00
Neurosciences

Description

Volume V deals with the problems of turnover in the nervous system. "Turnover" is defined in different ways, and the term is used in different contexts. It is used rather broadly in the present volume, and intentionally so. The turnover of macromolecules is only one aspect; here "turnover" in­ dicates the simultaneous and coordinated formation and breakdown of macromolecular species. The complexities of cerebral protein turnover are shown in aseparate chapter dealing with the synthesis ofproteins, in another on breakdown, and in still another on the relationship ofthese two (showing how the two halves of turnover are controlled). The fact that most likely the two halves of protein turnover, synthesis and breakdown, are separated spatially and the mechanisms involved are different further emphasizes the complexity of macromolecular turnover. "Turnover" is used in a different context when the turnover of a cycle is discussed; but he re again a number of complex metabolic reactions have to be interrelated and controlled; some such cycles are discussed briefly in this volume, additional cycles have been discussed with metabolism, and some cycles still await elucidation or discovery.

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