ENGLISH

HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols

By Oliver H. Krämer (eds.)

Book information

Publisher
Humana Press
Year
2017
ISBN
978-1-4939-6527-4, 978-1-4939-6525-0
DOI
10.1007/978-1-4939-6527-4
Language
english
Format
PDF
Filesize
13 MB (13960616 bytes)
Series
Methods in Molecular Biology 1510
Edition
1
Pages
XIV, 415\403
Time added
2016-12-08 02:00:00
Protein Science

Description

This detailed collection covers how the biological functions of histone deacetylases (HDACs) and histone acetyltransferases (HATs) can be detected in various experimental settings, both in vivo and in vitro. The book also covers the generation and specificity of deacetylase inhibitors and how such agents can be used to test experimental hypotheses. Written for the popular Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols serves as an ideal guide to this vital area of study.

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