Chemistry of Heterocyclic Compounds. Volume 5. Condensed Pyridazine and Pyrazine Rings (Cinnolines, Phthalazines, and Quinoxalines)

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Interscirnce Publishers, Inc., 1953. — 395 p.The Chemistry of Heterocyclic Compounds has been published since 1950 under the initial editorship of Arnold Weissberger, and later, until his death in 1984, under the joint editorship of Arnold Weissberger and Edward C. Taylor. In 1997, Peter Wipf joined Prof. Taylor as editor. This series attempts to make the extraordinarily complex and diverse field of heterocyclic chemistry as organized and readily accessible as possible. Each volume has traditionally dealt with syntheses, reactions, properties, structure, physical chemistry, and utility of compounds belonging to a specific ring system or class (e.g., pyridines, thiophenes, pyrimidines, threemembered ring systems). This series has become the basic reference collection for information on heterocyclic compounds.Contents Cinnolines General Introduction to Cinnoline Derivatives. Preparation and Properties of Cinnoline 4-Aryl-, 4-Acyl-, and 4-Carboxy-Cinnolines 4-Methylcinnolines 4-Hydroxycinnolines 4-Chloro-, 4-Alkoxy-, and 4-Phenoxycinnolines 4-Aminocinnolines Cinnoline Quaternary Salts Reduced Cinnolines Cinnolines Containing Additional Fused Rings Phthalazines Phthalazines Unsubstituted in the Hetero Ring 1-Alkyl-, 1-Aryl-, and 1,4-Diarylphthalazines 1-Hydroxyphthalazines Alkyl, Aryl, and Acyl Derivatives of 4-(1-)Hydroxyphthalazines 1-Hydroxy-3-Aryl-3,4-Dihydrophthalazine-4-Acetic Acids 3-Aryl-1-Ketophthalazines Methylated Derivatives of 3-Aryl-1-Ketophthalazines 1,4-Dihydroxyphthalazines Monoalkyl and Monoacyl Derivatives of 1,4-Dihydroxyphthalazines Dialkyl and Diacyl Derivatives of 1,4-Dihydroxyphthalazines 1-Halogeno- and 1,4-Dihalogenophathalazines 1-Aminophthalazines Reduced Phthalazines Condensed Phthalazines and Azaphthalazines Quinoxalines Preparation of Quinoxalines from Primary Aromatic O-Diamines and 1,2-Dicarbonyl Compounds Quinoxalines Unsubstituted in the Hetero Ring Quinoxaline N-Oxides 2-Hydroxy- and 2,3-Dihydroxyquinoxalines Quinoxaline-2-Aldehydes Quinoxaline-2-Carboxylic and -2,3-Dicarboxylic Acids 2-Chloro- and 2,3-Dichloroquinoxalines 2-Amino- and 2,3-Diaminoquinoxalines 2-Alkoxy-, 2,3-Dialkoxy-, and 2,3-Diaryloxyquinoxalines 2-Methyl- and 2,3-Dimethylquinoxalines Quinoxaline Quaternary Salts Formation of Quinoxalines from Compounds Containing a Furan Ring 2-Polyhydroxyalkaylquinoxalines Reduced Quinoxalines Condensed Quinoxalines Azaquinoxalines Appendix I. Ultraviolet Absorption Spectra of Cinnoline and Quinoxaline Derivatives Appendix II. Basic Strengths of Cinnoline, Phthalazine, and Quinoxaline Derivatives Appendix III. Antibacterial and Parasiticidal Activities of Cinnoline and Quinoxaline Derivatives Subject Index