The Ethics of Research with Human Subjects: Protecting People, Advancing Science, Promoting Trust

Description

This book provides a framework for approaching ethical and policy dilemmas in research with human subjects from the perspective of trust. It explains how trust is important not only between investigators and subjects but also between and among other stakeholders involved in the research enterprise, including research staff, sponsors, institutions, communities, oversight committees, government agencies, and the general public. The book argues that trust should be viewed as a distinct ethical principle for research with human subjects that complements other principles, such as autonomy, beneficence, non-maleficence, and justice. The book applies the principle of trust to numerous issues, including informed consent, confidentiality, risk minimization, risks and benefits, protection of vulnerable subjects, experimental design, research integrity, and research oversight.This work also includes discussions of the history of research involving human subjects, moral theories and principles, contemporary cases, and proposed regulatory reforms. The book is useful for undergraduate and graduate students studying ethical policy issues related to research with human subjects, as well as for scientists and scholars who are interested in thinking about this topic from the perspective of trust. Front Matter ....Pages i-xiii Introduction (David B. Resnik)....Pages 1-12 Historical Background (David B. Resnik)....Pages 13-51 Moral Theory (David B. Resnik)....Pages 53-85 Trust as a Foundation for Research with Human Subjects (David B. Resnik)....Pages 87-111 Informed Consent (David B. Resnik)....Pages 113-147 Privacy and Confidentiality (David B. Resnik)....Pages 149-163 Risks (David B. Resnik)....Pages 165-191 Benefits (David B. Resnik)....Pages 193-213 Vulnerable Subjects (David B. Resnik)....Pages 215-234 Research Integrity (David B. Resnik)....Pages 235-256 Regulatory Reform (David B. Resnik)....Pages 257-270 Conclusion (David B. Resnik)....Pages 271-277 Back Matter ....Pages 279-316