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Current Topics in Cellular Regulation: Volume 30 is a collection of papers that deals with eukaryotic DNA methylation, gene expression, regulation of nitrogenase activity, and the recognition of DNA by Type II restriction enzymes. Other papers discuss the mitochondrial Krebs cycle, enzyme mechanisms, transducin, and calcium-dependent cellular processes. One paper explains that methylation and demethylation of the DNA are complicated active processes, involving many aspects of the genome. The paper also notes that within the gross changes in methylation patterns, specific CpG sites play important roles in the expression or shutdown of target genes. Another paper concludes that, mono-ADP ribosylation being a mechanism of action of the diphtheria toxin, ADP ribosylation plays a role in normal cell metabolism by regulating the activity of key enzymes. One paper explains the significance of restriction enzymes into the nature of DNA-protein interactions; as well as the enzyme's possible role in discriminating between alternative DNA sequences. Biochemists, cellular researchers, micro-biologists, bio-physicists, and academicians involved in the study of cellular biology will find the collection very useful. Content: Front MatterPage iii Copyright pagePage iv Eukaryotic DNA Methylation and Gene ExpressionPages 1-21A. WEISSBACH, C. WARD, A. BOLDEN Regulation of Nitrogenase Activity by Reversible ADP RibosylationPages 23-56PAUL W. LUDDEN, GARY P. ROBERTS Recognition of DNA by Type II Restriction EnzymesPages 57-104S. PAUL BENNETT, STEPHEN E. HALFORD The Intracellular Site of Action of Insulin: The Mitochondrial Krebs CyclePages 105-142CHANDRA MOHAN, PAUL J. GEIGER, SAMUEL P. BESSMAN Nonequilibrium Isotope Exchange Methods for Investigating Enzyme MechanismsPages 143-169ATHEL CORNISH-BOWDEN Transducin: A Signaling Switch Regulated by Guanine NucleotidesPages 171-202YEE-KIN HO, VIJAY N. HINGORANI, SAMUEL E. NAVON, BERNARD K.-K. FUNG Coordinate Interactions of Cyclic Nucleotide and Phospholipid Metabolizing Pathways in Calcium-Dependent Cellular ProcessesPages 203-242SUZANNE G. LAYCHOCK IndexPages 243-252