ENGLISH

The experimental research (in vitro) of carrageenans and fucoidans to decrease activity of hantavirus

Book information

Language
english
Format
PDF
Filesize
668 kB (683705 bytes)
Pages
\7
Topic
Biology Virology
Library
twirpx
Time added
2017-08-07 07:01:42

Description

Статья. Опубликована в Food and Environmental Virology — 2016. — Т. 8. — №2. — С. 120-124. — DOI 10.1007/s12560-016-9233-9.The effect of carrageenans and fucoidans on the activity of Hantavirus is studied. It has been found that among carrageenans a significant antiviral effect is exerted by the ι-type, which decreases the viral titer by 2.5 log focus forming units per mL; among fucoidans, by a preparation from Laminaria cichorioides, which reduces the number of infected cells from 27.0 to 5.3 after pretreatment of both the macrophage culture and Hantavirus. The antiviral effect of fucoidan from Laminaria japonica is shown to grow in direct proportion to the increase of dose of the preparation.

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