ENGLISH

Muscarinic Receptor: From Structure to Animal Models

By Jaromir Myslivecek , Jan Jakubik

Book information

Publisher
Humana Press
Year
2015
ISBN
1493928570, 9781493928576
DOI
10.1007/978-1-4939-2858-3
ISSN
0893-2336
LCC
2015945343
Language
english
Format
PDF
Filesize
9 MB (9844769 bytes)
Series
Neuromethods 107
Pages
xii+287\301
Topic
Medicine Neurology
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2015-08-09 16:16:24
Neurosciences

Description

This volume provides methods for characterization of muscarinic receptor in crystallography studies that advanced our understanding of structural properties and activation mechanism of muscarinic receptors and are cornerstone in molecular modeling and computer‑based approaches to study muscarinic receptors. Muscarinic Receptor: From Structure to Animal Models guides readers through binding techniques, protocols to investigate molecular properties of muscarinic receptors, protocols to study muscarinic receptors in the central nervous system using autoradiography and PET studies and protocols on animals with knock-out and knock-in muscarinic genes to study role of muscarinic receptors in physiology and behavior. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Muscarinic Receptor: From Structure to Animal Models aims to ensure successful results in the further study of this vital field.

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