Unknown Title

Description

002_453563b......Page 1 002_453566e......Page 3 002_453567f......Page 4 002_453568a......Page 5 002_453570a......Page 7 002_453573a......Page 9 002_453575a......Page 11 002_453576a......Page 12 002_453577a......Page 13 002_453578a......Page 14 002_453581a......Page 17 002_453583a......Page 19 002_453586d......Page 22 002_453587a......Page 23 002_453588a......Page 24 002_453592a......Page 27 002_453594a......Page 29 002_453595a......Page 30 002_453596a......Page 31 002_453597a......Page 32 002_453598a......Page 33 002_453601a......Page 35 002_453603a......Page 37 002_453604a......Page 38 002_453606a......Page 40 Abstract......Page 42 Figure 2 Genetic variation in patterns of sex allocation.......Page 43 Figure 4 Sex ratio varies with the genetic diversity of P. chabaudi infections.......Page 44 Figure 6 Sex ratios of focal genotypes during the post-peak phase of infections.......Page 45 References......Page 46 Analyses......Page 48 Dynamics of influenza genetic diversity......Page 49 Figure 2 A ’source-sink’ model for the evolution of influenza A virus.......Page 50 Figure 4 Differences in phylogenetic history among segments of H3N2 influenza A virus.......Page 51 References......Page 52 Methods References......Page 54 Abstract......Page 55 Figure 1 B. fragilis colonization requires PSA for protection from experimental colitis.......Page 56 Figure 2 Purified PSA protects against experimental colitis.......Page 57 Figure 4 PSA induces Il10 expression in TNBS-treated animals and inhibits TNF-a production in primary cultured cells through IL-10 production.......Page 58 Figure 5 IL-10 is required for PSA-mediated protection from intestinal inflammation and experimental colitis.......Page 59 Abstract......Page 61 References......Page 63 Figure 1 The infrared ring around SGR 1900+14.......Page 62 Abstract......Page 64 References......Page 67 Figure 1 Phase diagram of jamming: theory.......Page 65 Figure 4 Phase diagram of jamming: simulations.......Page 66 Abstract......Page 68 References......Page 72 Methods References......Page 73 Figure 1 Quantum phase transition, device and conductance characteristics.......Page 69 Figure 3 Singlet-triplet quantum phase transition and universal scaling.......Page 70 Figure 4 Kondo effects in the singlet and triplet states.......Page 71 Figure 1 Slab models and calculated surface energies of anatase TiO2 (001) and (101) surfaces.......Page 74 References......Page 77 Methods References......Page 78 Figure 2 SEM images and statistical data for the size and truncation degree of anatase single crystals.......Page 75 Figure 4 Confirmation of the spatial distribution of F atoms in anatase single crystals.......Page 76 Abstract......Page 79 References......Page 81 Figure 2 Values of d13C and d18O for Nuccaleena Formation and Reynella Member cements and veins.......Page 80 Figure 1 Filtering out the ENSO and COWL signatures from the global-mean temperature time series.......Page 83 Figure 4 The HadSST2, ICOADS and country-of-origin time series.......Page 85 Methods......Page 87 Table 1 Correlations between indicated time series......Page 84 Abstract......Page 88 Figure 3 Materpiscis gen. nov.......Page 90 Methods References......Page 91 Figure 2 Holotype of Materpiscis attenboroughi gen. et sp. nov. (WAM 07.12.1).......Page 89 Figure 1 A highly diverse and abundant epilithic and endolithic microbial community exists on basaltic lavas from the East Pacific Rise.......Page 92 Phylogenetic analysis......Page 94 References......Page 95 Methods References......Page 96 Figure 3 Relative bacterial richness from several environmental studies shown through rarefaction analyses.......Page 93 Figure 1 Oleate increases the formation of lipid droplets in Drosophila S2 cells.......Page 97 References......Page 100 Figure 3 Phosphatidylcholine content regulates the size and abundance of lipid droplets.......Page 98 Figure 4 ArfI-COPI complex members function in the formation of lipid droplets.......Page 99 Abstract......Page 102 Figure 4 p110a is a positive regulator of RhoA in endothelial cells.......Page 105 Endothelial cell proliferation in vivo......Page 107 Methods References......Page 108 Figure 2 p110a is the main provider of PI3K signalling in endothelial cells under basal and VEGF-A-stimulated conditions.......Page 103 Figure 3 p110a controls endothelial cell migration in vitro and in vivo.......Page 104 Abstract......Page 109 References......Page 113 Methods References......Page 114 Figure 1 Analysis of the B-cell response induced by influenza vaccination.......Page 110 Figure 3 High-affinity mAbs generated from single influenza-specific ASCs.......Page 111 Table 1 Characteristics of anti-influenza antibodies......Page 112 Abstract......Page 115 References......Page 119 Quantification of vascular permeability, serum TNF-a and virus titre in infected mice......Page 120 Methods References......Page 121 Figure 2 CLEC5A is essential for DV-induced DAP12 phosphorylation, but not for DV replication.......Page 116 Figure 3 CLEC5A is critical for DV-mediated secretion of TNF-a but not that of IFN-a.......Page 117 Figure 4 Anti-mCLEC5A mAbs prevents DV-induced vascular leakage and lethality in STAT1-deficient mice.......Page 118 Figure 1 ATM-dependent stabilization and phosphorylation of hSSB1 after ionizing radiation.......Page 122 Figure 4 hSSB1 is required for efficient DNA repair.......Page 125 D-loop assay......Page 127 Figure 2 hSSB1 localizes to DNA repair foci after ionizing radiation.......Page 123 Figure 3 hSSB1 inhibition results in defective ionizing-radiation-induced checkpoint activation and defective ATM signalling.......Page 124 Figure 1 Alterations in HP1-b dynamics and localization accompany its mobilization after DNA damage.......Page 128 Figure 5 HP1-b mobilization by CK2 promotes H2AX phosphorylation.......Page 131 Methods References......Page 133 Figure 2 Thr 51 substitution or phosphorylation alter the localization and dynamics of HP1-b by disrupting a hydrogen-bond network essential for the HP1-H3K9me interaction.......Page 129 Figure 4 Inhibition of CK2 suppresses the phosphorylation of HP1-b on Thr 51 and mobilization after DNA damage.......Page 130 002_453687a......Page 134 002_453691a......Page 138 002_nj7195-693a......Page 140 002_nj7195-694c......Page 141 002_453696a......Page 142