Aptamers: Biotechnological Applications of a Next Generation Tool

Description

The book discusses the basics of aptamers and the advent of aptamer-based technology in recent times. The book covers the diverse applications of aptamers, such as in detection of animal and plant pathogens, disease diagnosis and therapeutics, environmental contamination detection etc. Besides these applications, the book also describes the use of these synthetic or modified DNA, as drug delivery vehicles. The different chapters describe how the binding capacity and specificity of aptamers can be exploited in various ways. The book also discusses how these attributes of aptamers can outdo the antibody technology in biomedical and diagnostic solutions. This crisp and concise book gives the readers an insight into the most recent biotechnological applications of aptamers. ​ Front Matter ....Pages i-xxi Aptamer: The Science of Synthetic DNA (Abhishek Parashar, Munna Lal Yadav, Gulab Singh Yadav, Ram Krishan Saini)....Pages 1-18 Recent Updates for Isolation of Aptamers for Various Biothreat Agents Using Different Strategies and Their Role in Detection Applications (Vijay Kumar, Anchal Sharma)....Pages 19-36 Aptamer: A Futuristic Approach in Diagnosis Rivaling Antibodies (Ruchi Mutreja, Pardeep Kumar, Anupama Semwal, Shubham Jain, Rajat Dhyani, Rupesh Agarwal et al.)....Pages 37-57 Aptamer: Apt System for Target-Specific Drug Delivery (Meenu Goyal, Citu, Nidhi Singh, Varsha Singla, Ankit Singla)....Pages 59-71 Aptamers: Novel Therapeutic and Diagnostic Molecules (Paavan Singhal, Anita Rani Gill, Preeti K. Sharma, Rakesh Kumar, Nabin Bhusal, Amandeep Kaur et al.)....Pages 73-89 Different Approaches for Aptamer Conjugated Drugs Preparation (Abhishek Parashar, Kush Kumar Pandey, Munna Lal Yadav)....Pages 91-100 Nucleic Acid Guided Molecular Tool for In-Vivo Theranostic Applications (Shahnawaz Ahmad Baba, Ruchi Mutreja, Arun Beniwal, Shubham Jain, Ekta Yadav, Tamoghna Ghosh et al.)....Pages 101-122 Current Development and Future Prospects of Aptamer Based Protein Targeting (Vivek Kumar, Hoime Banerjee)....Pages 123-131 Aptasensor-Possible Design and Strategy for Aptamer Based Sensor (Jyoti Yadav, Ankush, Khushboo, Mony Thakur, Karuna Yadav, Manisha Sharma et al.)....Pages 133-154 Aptamer-Based Biosensors for Detection of Environmental Pollutants (Meenu Goyal, Ankush, Mukesh R. Jangra, Ritu Batra, Pardeep Kumar)....Pages 155-167 Role of Aptamers in Plant Defense Mechanism Against Viral Diseases (Pawan K. Yadav, Sunil Kumar, Sanjay Yadav, Sandeep Kumar)....Pages 169-174 Aptamer: A Next Generation Tool for Application in Agricultural Industry for Food Safety (Gulab Singh Yadav, Abhishek Parashar, Neeraj K. Aggarwal)....Pages 175-186