ENGLISH

Protein Tyrosine Phosphatases: Methods and Protocols

By Rafael Pulido

Book information

Publisher
Humana Press
Year
2016
ISBN
1493937448, 9781493937448
DOI
10.1007/978-1-4939-3746-2
ISSN
1064-3745
Language
english
Format
PDF
Filesize
16 MB (16710128 bytes)
Series
Methods in Molecular Biology 1447
Pages
xii+402\415
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2016-08-13 14:19:05
Protein Science

Description

This book provides coverage, methodology, and laboratory protocols on the more essential aspects of protein tyrosine phosphatase (PTP) function and regulation, including the use of standardized in vitro functional assays, suitable cell systems, and animal and microorganism models. Chapters covering state-of-the-art technical approaches suitable to decipher the physiologic roles of PTPs, and their involvement in tissue-specific functions, are also included, which will be of utility for both newcomers and experienced researchers in the field of tyrosine- and phosphoinositide- phosphorylation/dephosphorylation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein Tyrosine Phosphatases: Methods and Protocols aims to aid researchers in better defining the common and individual features of the PTP family members and translating this knowledge into PTP-based therapy for human disease.

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