ENGLISH

Biological Modulation of Solid Tumours by Interferons

By K. Pummer (auth.) , Karl Pummer M.D. (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
1994
ISBN
978-3-642-78868-0, 978-3-642-78866-6, 3-540-57764-5, 0-387-57764-5
DOI
10.1007/978-3-642-78866-6
Language
english
Format
PDF
Filesize
7 MB (7653996 bytes)
Series
ESO Monographs
Edition
1
Pages
75\78
Time added
2013-12-12 02:00:00
Oncology; Immunology

Description

In the 1960s, it was reported that interferons have antitumour activity in different experimental models. Since that time, numerous studies have been performed to elucidate the various mechanisms of action that have been proposed. However, there is much controversy in the literature and promising preclinical findings failed to translate into substantial clinical progress. The present book gives a critical overview of current knowledge of how interferons act in solid tumours. For this purpose, after two chapters of general aspects of interferon action and interaction, selected solid tumours which are commonly considered difficult to treat in advanced stages are discussed with respect to both preclinical data and clinical experience.

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