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Advances in Cell Culture, Volume 6 is a compilation of research papers in the field of cell culture. The contributions reflect the applications of cell culture to biotechnology, to the study of basic mechanisms of cellular behavior, and to the study of pathogens and diseases. This volume contains chapters that deal with the differentiation of human epidermal cells, cell injury, and regeneration in cell culture models; the description of the testing of anticancer compounds in cultured cells; and the interactions of cells and asbestos. Other contributions cover the production in plant tissue culture of the potent antimalarial drug, artemisinin; plant cell suspensions used for studying the mode of action of plant growth retardants; and the in vitro genetic manipulation of cereals and grasses. Also included is a biographical sketch of Nobel Laureate Renato Dulbecco, whose pioneering work on mammalian cell layers has had an enormous impact on cell culture and virology. Cell biologists and researchers who use in vitro techniques will find the book highly informative and insightful. Content: Front MatterPage iii Copyright pagePage iv Contributors to Volume 6Page ix PrefacePage xiKARL MARAMOROSCH, GORDON H. SATO Renato DulbeccoPages xii-xviiKARL MARAMOROSCH Contents of Previous VolumesPages xix-xx Terminal Differentiation in Cultured human Epidermal CellsPages 1-33Elaine Fuchs, Kathryn Albers, Raphael Kopan Microvascular Endothelial Cells: Isolation, Identification, and CultivationPages 35-67Mary E. Gerritsen, William Carley, Anthony J. Milici The Production of Artemisinin in Artemisia annua L. Tissue CulturesPages 69-87Blanca C. Martinez, E. John Staba Plant Cell Suspensions for Screening and Studying the Mode of Action of Plant Growth RetardantsPages 89-136K. Grossmann Cultures of Mammary Epithelial Cells: Extracellular Matrix and Functional DifferentiationPages 137-159Joanne T. Emerman, Mina J. Bissell Cell Culture for Testing Anticancer CompoundsPages 161-197Regina L. Ruben Asbestos and TransfectionPages 199-260George R. Dubes Cell Injury, Differentiation, and Regeneration in Explant, Organ, and Cell Culture ModelsPages 261-289James H. Resau, Benjamin F. Trump In Vitro Genetic Manipulation of Cereals and GrassesPages 291-325Paul A. Lazzeri, Horst Lörz IndexPages 327-339
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