ENGLISH

Genetically Engineered Mice for Cancer Research: design, analysis, pathways, validation and pre-clinical testing

By Thomas Doetschman , L. Philip Sanford (auth.) , Jeffrey E. Green , Thomas Ried (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2012
ISBN
0387698035, 9780387698038
DOI
10.1007/978-0-387-69805-2
Google Books ID
ERrHqi9XncUC
Language
english
Format
PDF
Filesize
13 MB (13635248 bytes)
Edition
1
Pages
632\653
Orientation
yes
Scanned
no
Time added
2012-03-09 12:00:00
Cancer Research; Human Genetics; Laboratory Medici

Description

Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials.

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