Managing Myositis: A Practical Guide

Description

This comprehensive book serves as a guide in the day-to-day management of patients with idiopathic inflammatory myopathies (IIM), with a particular emphasis on adult dermatomyositis (DM), polymyositis (PM), juvenile dermatomyositis, necrotizing myositis, and inclusion body myositis. Practical in nature, it presents IIM concepts in a straightforward fashion, with high-quality figures, algorithms, and flowcharts supplementing each of the expertly authored chapters. The book begins with an introduction to myositis, providing an overview of the myositis basics and what type of patient is affected. Subsequent chapters are organized by the sequence in which a physician often manages myositis, from initial presentation and workup, to diagnosis, treatment, and finally prognostic and long-term outcome factors. The key differentials in various diagnostic studies are thoroughly examined, including electromyography, muscle biopsy, and MRI. Managing Myositis: A Practical Guide is an easy to-read, indispensable resource for internists, rheumatologists, dermatologists, pulmonologists, and neurologists. Front Matter ....Pages i-xx Introduction to Myositis (Adam Schiffenbauer, Frederick W. Miller)....Pages 1-6 Myositis Basics/Who Gets Myositis (Matthew J. S. Parker, Hector Chinoy, Robert G. Cooper, Janine A. Lamb)....Pages 7-15 Evaluating the Patient with Suspected Myositis (Rohit Aggarwal, Chester V. Oddis)....Pages 17-24 Asymptomatic HyperCKemia (Siamak Moghadam-Kia, Rohit Aggarwal)....Pages 25-35 Clinical Features of Myositis: Muscular Manifestations (Jiri Vencovsky)....Pages 37-46 Clinical Features of Myositis: Skin Manifestations (Peter B. Chansky, Victoria P. Werth)....Pages 47-55 Clinical Features of Myositis: Lung Manifestations (Sonye K. Danoff)....Pages 57-62 Clinical Features of Myositis: Cardiac Manifestations (Sangmee Bae, Christina Charles-Schoeman)....Pages 63-74 Clinical Features of Myositis: Arthritis, Raynaud Phenomenon, Constitutional (Kristina E. N. Clark, David A. Isenberg)....Pages 75-80 Clinical Features of Myositis: Juvenile Dermatomyositis (Adam M. Huber)....Pages 81-89 Making the Diagnosis of Myositis: Definition and Classification of Myositis (Valérie Leclair, Ingrid E. Lundberg)....Pages 91-98 Making the Diagnosis of Myositis: Electrodiagnostic Testing (David Lacomis)....Pages 99-108 Making the Diagnosis of Myositis: Muscle Biopsy and Interpretation (David Lacomis)....Pages 109-124 Making the Diagnosis of Myositis: Skin Biopsy and Interpretation (Inbal Sander)....Pages 125-130 Making the Diagnosis of Myositis: Lung Biopsy and Interpretation (Frank Schneider, Patty Chen)....Pages 131-144 Making the Diagnosis of Myositis: Muscle MRI (Jonas Lötscher, Balazs K. Kovacs, Ulrich A. Walker)....Pages 145-160 Making the Diagnosis of Myositis: Laboratory Testing in Myositis (Olivier Benveniste, Lucile Musset)....Pages 161-166 Role of ANA and Myositis Autoantibodies in Diagnosis (Neil J. McHugh, Ira N. Targoff)....Pages 167-174 Role of Myositis Autoantibodies in Management and Prognosis (Takahisa Gono, Masataka Kuwana)....Pages 175-180 Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP (Samera Vaseer, Ira N. Targoff)....Pages 181-192 Dermatomyositis-Associated Autoantibodies: TIF1-γ, NXP2, and MDA5 (Takahisa Gono, Masataka Kuwana)....Pages 193-198 Newly Described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60 (Zoe Betteridge, Neil J. McHugh)....Pages 199-207 Myositis Mimics: The Differential Diagnosis of Myositis (Harlan Michelle, Andrew L. Mammen)....Pages 209-223 Immune-Mediated Necrotizing Myopathy (IMNM) (Brittany Adler, Lisa Christopher-Stine)....Pages 225-235 Cancer-Associated Myositis (Albert Selva-O’Callaghan, Ernesto Trallero-Araguás, Iago Pinal-Fernandez)....Pages 237-245 Myositis-Associated Interstitial Lung Disease (Sonye K. Danoff)....Pages 247-256 Pregnancy in Myositis (Melinda Nagy-Vincze, Katalin Dankó)....Pages 257-266 Pathogenesis of Myositis (Dana P. Ascherman)....Pages 267-274 Management Considerations: Pharmacologic Intervention (Chester V. Oddis, Rohit Aggarwal)....Pages 275-283 Management Considerations: Juvenile Dermatomyositis (Jeffrey Dvergsten, Ann Reed)....Pages 285-298 Management Considerations: Refractory Skin Rash and Calcinosis (Matthew A. Lewis, David F. Fiorentino)....Pages 299-314 Management Considerations: Interstitial Lung Disease (Tracy J. Doyle, Paul F. Dellaripa)....Pages 315-322 Role of Exercise in the Management of Myositis (Helene Alexanderson, Malin Regardt)....Pages 323-334 Dietary Considerations in Myositis (Kun Huang, Rohit Aggarwal)....Pages 335-344 Distinguishing Disease Activity and Damage in Myositis (Rodolfo Curiel, Lisa G. Rider)....Pages 345-354 Back Matter ....Pages 355-364