Atlas of Ulcers in Systemic Sclerosis: Diagnosis and Management

Description

This Atlas examines skin ulcers in patients affected by systemic sclerosis. Although they are not life threatening, digital ulcers cause enormous pain, impact function and quality of life, and can lead to serious local complications such as gangrene, osteomyelitis, and permanent tissue loss. Knowledge and understanding of these ulcers is pivotal in everyday practice in order to arrive at an accurate early diagnosis, a correct analysis of ulcer characteristics, and an appropriate direct and systematic treatment. To that end, this book describes all the major characteristics of skin ulcers in systematic sclerosis, including classification, evaluation, and categorization. Richly illustrated for practical use, Atlas of Ulcers in Systemic Sclerosis: Diagnosis and Management is an essential resource for physicians and related professionals, residents, and graduate students in rheumatology, dermatology, and angiology. Front Matter ....Pages i-xi Front Matter ....Pages 1-1 Defining Digital Ulcers in Systemic Sclerosis: The State of the Art (Daniel E. Furst, Yossra Atef Suliman, Christopher P. Denton, Marco Matucci-Cerinic)....Pages 3-5 Digital Ulcerations and Classification of SSc Subsets and Overlap Syndromes (Carina Gaertner, Oana-Diana Persa, Nicolas Hunzelmann)....Pages 7-13 Classification of Digital and Lower Limb Ulcers in SSc (Jelena Blagojevic)....Pages 15-24 Front Matter ....Pages 25-25 Vascular Mechanisms of Systemic Sclerosis (Janine Schniering, Britta Maurer, Oliver Distler)....Pages 27-37 Introduction to Wound Healing and Tissue Repair (Sabine A. Eming)....Pages 39-41 Front Matter ....Pages 43-43 Raynaud’s Phenomenon and Ulcers (Michael Hughes, Marina E. Anderson, Ariane L. Herrick)....Pages 45-62 Capillary Microscopy (Maurizio Cutolo, Alberto Sulli, Vanessa Smith)....Pages 63-78 Digital Ulcers, Vasculopathy and Internal Organ Involvement (Yannick Allanore)....Pages 79-85 Front Matter ....Pages 87-87 Fistulas (Guya Piemonte, Francesca Braschi, Laura Rasero)....Pages 89-94 Infections, Cellulitis, and Osteomyelitis (Silvia Bellando-Randone, Gemma Lepri)....Pages 95-98 Digital Loss (Gangrene, Amputation, Autoamputation) (Jelena Blagojevic)....Pages 99-103 Pain (Felice Galluccio)....Pages 105-107 Clinical Impact of Digital Ulcers (Paul Legendre, Luc Mouthon)....Pages 109-113 Calcinosis (Francesca Bartoli, Laura Cometi, Marco Matucci-Cerinic)....Pages 115-118 Front Matter ....Pages 119-119 The Team and the Assessment (Cosimo Bruni, Tiziana Pucci, Laura Rasero, Christopher P. Denton)....Pages 121-123 Diagnostic Tools (Yannick Allanore)....Pages 125-129 Front Matter ....Pages 131-131 Differential Diagnosis: Vasculitis, Rheumatoid Arthritis, Behçet’s Disease, and Thromboembolism (Benjamin Chaigne, Loïc Guillevin)....Pages 133-142 Front Matter ....Pages 143-143 The Local Treatment: Methodology, Debridement and Wound Bed Preparation (Guya Piemonte, Laura Benelli, Francesca Braschi, Laura Rasero)....Pages 145-159 Wound Dressing for Digital Ulcers in Systemic Sclerosis (Silvia Bellando-Randone, Tiziana Pucci, Laura Rasero, Christopher P. Denton, Marco Matucci-Cerinic)....Pages 161-164 Front Matter ....Pages 165-165 Ulcer Healing and Prevention in Systemic Sclerosis (Cosimo Bruni, Silvia Bellando-Randone, Christopher P. Denton, Marco Matucci-Cerinic)....Pages 167-171 Surgical Approaches Including Sympathectomy (Lindsay Muir, Ariane L. Herrick)....Pages 173-182 Antibiotic Treatment (Jasmin Raja, Voon H. Ong)....Pages 183-192 Alternative Therapeutic Approaches in Skin Ulcers Due to Systemic Sclerosis (Nabil George, Todd Kanzara, Kuntal Chakravarty)....Pages 193-205 Front Matter ....Pages 207-207 Adipose-Derived Stem Cells to Facilitate Ulcer Healing: Future Strategies (Nicoletta Del Papa, Eleonora Zaccara, Gabriele Di Luca, Wanda Maglione)....Pages 209-215 Front Matter ....Pages 217-217 Atlas of Digital Ulcers and Lesions (Marco Matucci-Cerinic, Christopher P. Denton, Tiziana Pucci, Francesca Braschi, Claudia Fantauzzo, Lucia Paganelli)....Pages 219-231 Back Matter ....Pages 233-238