Lipidomics in Health & Disease: Methods & Application

Description

This volume covers the emerging area of science, Clinical Lipidomics, which is theapplication of lipidology to the understanding of physiological and pathophysiological changes of lipidomes, with a special focus on lipidomic profiles in human diseases. Lipidomics is widely used to map lipid molecular species in a biological system. Clinical lipidomic analysis has demonstrated the comprehensive characterization of molecular lipids in various severities, durations, and therapies as a critical tool in identification and validation of disease-specific biomarkers. This volume on Clinical Lipidomics will add to the literature and help advance the knowledge of the pathogenesis, diagnosis, prevention and treatment of diseases. Front Matter ....Pages i-vi Clinical Lipidomics: A Critical Approach for Disease Diagnosis and Therapy (Xiangdong Wang)....Pages 1-5 The Role of Lipid Metabolism in the Development of Lung Cancer (Lixin Wang, Weiling Huang, Xiu-Min Li)....Pages 7-19 Bioinformatics of Embryonic Exposures: Lipid Metabolism and Gender as Biomedical Variables (K. K. Linask)....Pages 21-37 An Evaluation of Multivariate Data Analysis Models for Lipidomic Parameters from Patients with Metabolic Syndrome Undergoing Remedial Treatment (D. Farabos, C. Wolf, R. Chapier, A. Lamaziere, Peter J. Quinn)....Pages 39-53 Lipidomics in Carotid Artery Stenosis: Further Understanding of Pathology and Treatment (Wei Zhang, Xiushi Zhou, Daqiao Guo, Weiguo Fu, Lixin Wang)....Pages 55-72 Metabolomics of Immunity and Its Clinical Applications (Jing Qiu, Fangming Liu, Duojiao Wu)....Pages 73-95 Urinary Lipidomics (Phornpimon Tipthara, Visith Thongboonkerd)....Pages 97-111 Breast Cancer and Lipid Metabolism (Chunfa Huang, Yuntao Li, Yifan Tu, Carl E. Freter)....Pages 113-135 Association of Circulating Oxidized Lipids with Cardiovascular Outcomes (Irena Levitan, Ibra S. Fancher, Evgeny Berdyshev)....Pages 137-154 Lipidomics: Mass Spectrometry Based Untargeted Profiling and False Positives (Xiaohui Liu, Lina Xu, Xueying Wang, Yupei Jiao)....Pages 155-176 Phospholipid and Phospholipidomics in Health and Diseases (Tanxi Cai, Fuquan Yang)....Pages 177-202 Back Matter ....Pages 203-204