Optimization of Behavioral, Biobehavioral, and Biomedical Interventions

Description

Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This book provides additional information on a principled empirical framework for developing interventions that are more effective, efficient, economical, and scalable. This framework is introduced in the monograph, "Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy (MOST)" by Linda M. Collins (Springer, 2018). The present book is focused on advanced topics related to MOST. The chapters, all written by experts, are devoted to topics ranging from experimental design and data analysis to development of a conceptual model and implementation of a complex experiment in the field. Intervention scientists who are preparing to apply MOST will find this book an important reference and guide for their research. Fields to which this work pertains include public health (medicine, nursing, health economics, implementation sciences), behavioral sciences (psychology, criminal justice), statistics, and education. Front Matter ....Pages i-xii Using the Multiphase Optimization Strategy (MOST) to Develop an Optimized Online STI Preventive Intervention Aimed at College Students: Description of Conceptual Model and Iterative Approach to Optimization (Kari C. Kugler, David L. Wyrick, Amanda E. Tanner, Jeffrey J. Milroy, Brittany Chambers, Alice Ma et al.)....Pages 1-21 Implementing Factorial Experiments in Real-World Settings: Lessons Learned While Engineering an Optimized Smoking Cessation Treatment (Megan E. Piper, Tanya R. Schlam, David Fraser, Madeline Oguss, Jessica W. Cook)....Pages 23-45 Multilevel Factorial Designs in Intervention Development (Inbal Nahum-Shani, John J. Dziak)....Pages 47-87 Experimental Designs for Research on Adaptive Interventions: Singly and Sequentially Randomized Trials (Daniel Almirall, Inbal Nahum-Shani, Lu Wang, Connie Kasari)....Pages 89-120 Intensively Adaptive Interventions Using Control Systems Engineering: Two Illustrative Examples (Daniel E. Rivera, Eric B. Hekler, Jennifer S. Savage, Danielle Symons Downs)....Pages 121-173 Coding and Interpretation of Effects in Analysis of Data from a Factorial Experiment (Kari C. Kugler, John J. Dziak, Jessica Trail)....Pages 175-205 Optimizing the Cost-Effectiveness of a Multicomponent Intervention Using Data from a Factorial Experiment: Considerations, Open Questions, and Tradeoffs Among Multiple Outcomes (John J. Dziak)....Pages 207-267 Investigating an Intervention’s Causal Story: Mediation Analysis Using a Factorial Experiment and Multiple Mediators (Rachel A. Smith, Donna L. Coffman, Xun Zhu)....Pages 269-294 Back Matter ....Pages 295-301