Chirality in Drug Research, Volume 33

Description

Content: Chapter 1 Chiral Drugs from a Historical Point of View (pages 1–26): Joseph GalChapter 2 Stereoselective Synthesis of Drugs – An Industrial Perspective (pages 27–65): Hans?Jurgen FederselChapter 3 Aspects of Chirality in Natural Products Drug Discovery (pages 67–94): Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt and Ansgar SchuffenhauerChapter 4 Biotransformation Methods for Preparing Chiral Drugs and Drug Intermediates (pages 95–123): Michael Muller and Marcel WubboltsChapter 5 Resolution of Chiral Drugs and Drug Intermediates by Crystallisation (pages 125–154): Kazuhiko Saigo and Kenichi SakaiChapter 6 Isolation and Production of Optically Pure Drugs by Enantioselective Chromatography (pages 155–187): Eric FrancotteChapter 7 Stereoselective Chromatographic Methods for Drug Analysis (pages 189–260): Norbert M. Maier and Wolfgang LindnerChapter 8 Capillary Electrophoresis Coupled to Mass Spectrometry for Chiral Drugs Analysis (pages 261–281): Serge Rudaz and Jean?Luc VeutheyChapter 9 Powerful Chiral Molecular Tools for Preparation of Enantiopure Alcohols and Simultaneous Determination of Their Absolute Configurations by X?Ray Crystallography and/or 1H NMR Anisotropy Methods (pages 283–321): Nobuyuki HaradaChapter 10 Keywords in Chirality Modeling: Molecular Modeling of Chirality – Software and Literature Research on Chirality in Modeling, Chirality in Docking, Chiral Ligand–Receptor Interaction and Symmetry (pages 323–340): Gerd Folkers, Mine Yarim and Pavel Pospisil