ENGLISH

Prodrugs and Targeted Delivery: Towards Better ADME Properties

By Raimund Mannhold , Hugo Kubinyi , Gerd Folkers(eds.)

Book information

Year
2010
ISBN
9783527326037, 9783527633166
DOI
10.1002/9783527633166
Language
english
Format
PDF
Filesize
4 MB (4606035 bytes)
Series
Methods and Principles in Medicinal Chemistry
Pages
507\507
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00

Description

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.

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