Chromatin Proteins and Transcription Factors as Therapeutic Targets

Description

Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Content: CopyrightPage iv ContributorsPages ix-xi PrefacePages xiii-xviRossen Donev Chapter One - Targeting Chromatin Remodeling in Inflammation and FibrosisPages 1-36J. Yang, B. Tian, A.R. Brasier Chapter Two - HMGB1 Protein: A Therapeutic Target Inside and Outside the CellPages 37-76I. Ugrinova, E. Pasheva Chapter Three - Targeting IKK and NF-κB for TherapyPages 77-115J.K. Durand, A.S. Baldwin Chapter Four - NF-κB as a Therapeutic Target in Inflammatory-Associated Bone DiseasesPages 117-154T.-h. Lin, J. Pajarinen, L. Lu, A. Nabeshima, L.A. Cordova, Z. Yao, S.B. Goodman Chapter Five - The Functional Stability of FOXP3 and RORγt in Treg and Th17 and Their Therapeutic ApplicationsPages 155-189J. Ren, B. Li Chapter Six - The Complex Role of the ZNF224 Transcription Factor in CancerPages 191-222E. Cesaro, G. Sodaro, G. Montano, M. Grosso, A. Lupo, P. Costanzo Chapter Seven - Transcription Factors in Breast Cancer—Lessons From Recent Genomic Analyses and Therapeutic ImplicationsPages 223-273E. Zacksenhaus, J.C. Liu, Z. Jiang, Y. Yao, L. Xia, M. Shrestha, Y. Ben-David Chapter Eight - Transcription Factors as a Target for Vaccination Against Ticks and MitesPages 275-282O.A.E. Sparagano Chapter Nine - Elucidating the Mutational Landscape in Hepatocyte Nuclear Factor 1β (HNF1B) by Computational ApproachPages 283-306P. Sneha, C.G.P. Doss Author IndexPages 307-360 Subject IndexPages 361-369