ENGLISH

Biotechnology, Products of Secondary Metabolism

By H. Kleinkauf , Hans von Döhren

Book information

Publisher
Wiley-VCH
Year
1997
ISBN
9783527283170, 3527283102
Open Library ID
OL9052161M
Language
english
Format
PDF
Filesize
49 MB (51744908 bytes)
Volume
Vol. 7
Edition
2
Pages
736\736
Library
duansci.com
Scanned
no
Time added
2010-05-17 00:23:50
Биологические дисциплины;Микробиология и биотехнол

Description

Products of secondary metabolism from fermentation and cell culture are mainly pharmaceuticals, ranging from traditional antibacterials like beta-lactams, new generation compounds like dalbaheptides and lantibiotics to immunomodulators and antitumor drugs. The major fields of application of these low volume/high price products are human and veterinary medicine as well as plant protection. In this volume functionally based screening approaches and the applications of molecular genetics in the discovery and process improvement of compounds are emphasized. Along with the exploitation of new sources the growing understanding of biosynthetic processes permits the identification of the genetic backgrounds. Topics included are: Novel Receptor-Active Compounds - Microbial Lipids - Microbial Siderophores - beta-Lactam Antibiotics - Peptide Antibiotics - Lantibiotics - Glycopeptide Antibiotics (Dalbaheptides) - Aminoglycosides - Products from Basidiomycetes - Cyclosporins - Secondary Products from Plant Cells - Antitumor Agents

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