Handbook of Nucleobase Complexes

Description

"This handbook describes methods of preparation, characterization, toxicity, and therapeutic indices of transition metal complexes of the naturally occurring heterocyclic nucleobases and their derivatives. Modes of coordination are listed together with the relevant spectral data and major methods of investigation. Where appropriate, the spectrum of the sample is included in the pertinent section on spectroscopy. Data on the uncomplexed bases, such as solubility, pK, accepted structure(s) in the solid state and solutions, and the natural occurrence of the base are also included. Volume II of this work provides the spectroscopic data to accompany Volume I. Volume II is divided into two sections: Section 1 summarizes the data and Section 2 is comprised of figures. In Section 1, the complexes are arranged according to the method of study. In Section 2, figures are listed by base type and follow the sequence of Volume I, mainly complexes of the pyrimidine bases, nucleosides and nucleotides, and then purine bases, nucleosides, and nucleotides."--Provided by publisher. Read more... Abstract: "This handbook describes methods of preparation, characterization, toxicity, and therapeutic indices of transition metal complexes of the naturally occurring heterocyclic nucleobases and their derivatives. Modes of coordination are listed together with the relevant spectral data and major methods of investigation. Where appropriate, the spectrum of the sample is included in the pertinent section on spectroscopy. Data on the uncomplexed bases, such as solubility, pK, accepted structure(s) in the solid state and solutions, and the natural occurrence of the base are also included. Volume II of this work provides the spectroscopic data to accompany Volume I. Volume II is divided into two sections: Section 1 summarizes the data and Section 2 is comprised of figures. In Section 1, the complexes are arranged according to the method of study. In Section 2, figures are listed by base type and follow the sequence of Volume I, mainly complexes of the pyrimidine bases, nucleosides and nucleotides, and then purine bases, nucleosides, and nucleotides."--Provided by publisher Content: Cover Title Page Copyright Page PREFACE ACKNOWLEDGMENTS FIGURE CREDITS AND ACKNOWLEDGMENTS NOTES FOR GUIDANCE METHODS OF STUDY KEY OF ABBREVIATIONS Methods of Study SECTION 1.1 Antitumor Activity SECTION 1.2 Circular Dichroism SECTION 1.3 Conductivity SECTION 1.4 Electron Spin Resonance Spectroscopy SECTION 1.5 High Performance Liquid Chromatography SECTION 1.6 Infrared Spectroscopy SECTION 1.7 Mossbauer Spectroscopy SECTION 1.8 [sup(1)]H Nuclear Magnetic Resonance SECTION 1.9 [sup(13)]C Nuclear Magnetic Resonance SECTION 1.10 [sup(31)]P Nuclear Magnetic Resonance SECTION 1.11 [sup(195)]Pt Nuclear Magnetic ResonanceSECTION 1.12 pK Measurements SECTION 1.13 Raman Spectroscopy SECTION 1.14 Thermal Studies SECTION 1.15 UV-VIS Spectroscopy SECTION 1.16 XPS SECTION 1.17 X-Ray Figures SECTION 2.1 Complexes Involving Pyrimidine Bases SECTION 2.2 Complexes Involving Pyrimidine Nucleosides SECTION 2.3 Complexes Involving Pyrimidine Nucleotides SECTION 2.4 Complexes Involving Purine Bases SECTION 2.5 Complexes Involving Purine Nucleosides SECTION 2.6 Complexes Involving Purine Nucleotides and Oligonucleotides References Index