ENGLISH

Irreversible electroporation

By Antoni Ivorra , Boris Rubinsky (auth.) , Boris Rubinsky (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2010
ISBN
3642054196, 9783540721093, 9783540793694, 9780387764948, 9783642054198
DOI
10.1007/978-3-642-05420-4
LCC
QP84.6 .B568 2007
Open Library ID
OL16678136M
Language
english
Format
PDF
Filesize
6 MB (6005395 bytes)
Series
Series in Biomedical Engineering
Edition
1
Pages
313\320
Topic
Technique
Library
duansci.com_Biology
Time added
2010-02-18 13:16:04
Biomedical Engineering; Electrophoresis; Oncology;Cellular and Medical Topics; MicrowavesRF and Optical Engineering

Description

This is an brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane. Sometimes this process leads to cell death, primarily when the electrical fields cause permanent permeabilization of the membrane and the consequent loss of cell homeostasis, in a process known as irreversible electroporation. This is an unusual mode of cell death that is not fully understood yet. While the phenomenon of irreversible electroporation may have been known for centuries it has become only recently rigorously considered in medicine for various applications of tissue ablation. A brief historical perspective of irreversible electroporation is presentedfollowed by general reviews on the theory and experiment fundamentals and by reports on the most recent theoretical, experimental and clinical studies.

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