Psychoneuroimmunology

Description

This fully-updated book provides systems-based methodologies and innovative technologies that can be used for solving complicated problems of complex systems. A wide range of theoretical and experimental approaches are introduced for practical applications, as the content explores the basic and novel concepts in psychoneuroimmunology (PNI), especially the relationships among stress, inflammation, and psychophysiological disorders, as well as various cutting-edge technologies and methods for PNI studies, including the utilizations of mouse models and vaccine models. In addition, this book focuses on translational medicine by applying PNI methods in clinical practice. As part of the Methods in Molecular Biology series, the chapters seek to provide a practical, state-of-the-art, and holistic view for the translation of PNI into better preventive and personalized medical practice. Authoritative and hands-on, Psychoneuroimmunology: Methods and Protocols, Second Edition will be of use to biomedical students and professionals at all levels who are interested in integrative studies in psychology, psychiatry, neuroscience, immunology, molecular biology, genetics, bioengineering, physiology, pathology, microbiology, systems biology, and clinical medicine. Front Matter ....Pages i-xi Front Matter ....Pages 1-1 Stress and Systemic Inflammation: Yin-Yang Dynamics in Health and Diseases (Qing Yan)....Pages 3-20 Intersections Between Neuroimmune and Microbiota (Colette G. Ngo Ndjom, Xavier F. Gonzalez, Harlan P. Jones)....Pages 21-35 Psychoneuroimmunology: The Experiential Dimension (Elling Ulvestad)....Pages 37-53 Ecological Context and Human Variation: Applying the Principles of Biological Anthropology to Psychoneuroimmunology (Eric C. Shattuck)....Pages 55-76 Neuroimmune Imbalances and Yin-Yang Dynamics in Stress, Anxiety, and Depression (Qing Yan)....Pages 77-85 Increasing Resilience to Traumatic Stress: Understanding the Protective Role of Well-Being (J. Tory Toole, Mark A. Rice Jr, Jordan Cargill, Travis J. A. Craddock, Barry Nierenberg, Nancy G. Klimas et al.)....Pages 87-100 Exploring the Diagnostic Potential of Immune Biomarker Co-expression in Gulf War Illness (Gordon Broderick, Mary Ann Fletcher, Michael Gallagher, Zachary Barnes, Suzanne D. Vernon, Nancy G. Klimas)....Pages 101-120 Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression (J. Tory Toole, Mark A. Rice Jr, Travis J. A. Craddock, Barry Nierenberg, Nancy G. Klimas, Mary Ann Fletcher et al.)....Pages 121-144 Neuroimmune Mechanisms of Depression in Adults with Heart Failure (Jessica A. Jiménez, Christine Tara Peterson, Paul J. Mills)....Pages 145-169 How to Monitor the Neuroimmune Biological Response in Patients Affected by Immune Alteration-Related Systemic Diseases (Paolo Lissoni, Franco Rovelli, Luigi Vigorè, Giusy Messina, Arianna Lissoni, Giorgio Porro et al.)....Pages 171-191 Front Matter ....Pages 193-193 Application of Chemogenetics and Optogenetics to Dissect Brain-Immune Interactions (Ben Korin, Asya Rolls)....Pages 195-208 Psychoneuroimmunology and Natural Killer Cells: The Chromium-Release Whole-Blood Assay (Mary Ann Fletcher, Zachary Barnes, Gordon Broderick, Nancy G. Klimas)....Pages 209-220 Mouse Testing Methods in Psychoneuroimmunology 2.0: Measuring Behavioral Responses (Albert E. Towers, Jason M. York, Tracy Baynard, Stephen J. Gainey, Gregory G. Freund)....Pages 221-258 The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions (Boris Šakić)....Pages 259-285 PET Imaging in Psychoneuroimmunology Research (Jonas Hannestad)....Pages 287-307 The Vaccination Model in Psychoneuroimmunology Research: A Review (Anna C. Whittaker)....Pages 309-326 Measuring Vaccine Responses in the Multiplex Era (Kieran Ayling, Kavita Vedhara, Lucy Fairclough)....Pages 327-340 Sculpting the Sculptors: Methods for Studying the Fetal Cholinergic Signaling on Systems and Cellular Scales (Martin G. Frasch, Patrick Burns, Javier Benito, Marina Cortes, Mingju Cao, Gilles Fecteau et al.)....Pages 341-352 Perinatal Psychoneuroimmunology: Protocols for the Study of Prenatal Stress and Its Effects on Fetal and Postnatal Brain Development (Martin G. Frasch, Carlos J. Baier, Marta C. Antonelli, Gerlinde A. S. Metz)....Pages 353-376 Back Matter ....Pages 377-381