Cell Biology and Translational Medicine, Volume 1: Stem Cells in Regenerative Medicine: Advances and Challenges

Description

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. With a goal to accelerate advances by timely information exchange, this new book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series is launched. Emerging areas of regenerative medicine and translational aspects of stem cells will be covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the first volume of a continuing series. Front Matter ....Pages i-viii Embryonic Stem Cells in Development and Regenerative Medicine (Ayşegül Doğan)....Pages 1-15 Adult Stem Cells and Medicine (Sinem Civriz Bozdağ, Meltem Kurt Yüksel, Taner Demirer)....Pages 17-36 Stem Cells in Regenerative Cardiology (Semih Arbatlı, Galip Servet Aslan, Fatih Kocabaş)....Pages 37-53 The Potency of Induced Pluripotent Stem Cells in Cartilage Regeneration and Osteoarthritis Treatment (Cormac Murphy, Ali Mobasheri, Zsuzsanna Táncos, Julianna Kobolák, András Dinnyés)....Pages 55-68 Pericytes: The Role of Multipotent Stem Cells in Vascular Maintenance and Regenerative Medicine (Toka A. Ahmed, Nagwa El-Badri)....Pages 69-86 Stem Cell Therapy: Repurposing Cell-Based Regenerative Medicine Beyond Cell Replacement (Eleonora Napoli, Trenton Lippert, Cesar V. Borlongan)....Pages 87-91 Stem Cells in Alzheimer’s Disease: Current Standing and Future Challenges (Haitham Salem, Gabriela D. Colpo, Antonio L. Teixeira)....Pages 93-102 Developments in Hematopoietic Stem Cell Expansion and Gene Editing Technologies (Dogacan Yucel, Fatih Kocabas)....Pages 103-125 Clinical Applications of Induced Pluripotent Stem Cells – Stato Attuale (Chavali Kavyasudha, Dannie Macrin, K. N. ArulJothi, Joel P. Joseph, M. K. Harishankar, Arikketh Devi)....Pages 127-149 Safety and Efficacy of Epigenetically Converted Human Fibroblasts Into Insulin-Secreting Cells: A Preclinical Study (Tiziana A. L. Brevini, Georgia Pennarossa, Elena F. M. Manzoni, Fulvio Gandolfi)....Pages 151-162 Back Matter ....Pages 163-168