Lung Stem Cell Behavior

Description

This book reviews stem cell behavior in the lung as it relates to regenerative medicine and stem cell therapeutics. Topics ranging from basic developmental mechanisms of various types of lung stem cells through the identification and properties of stem cell behavior and their potential applications in lung repair and regeneration, are discussed by an expert in the field. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in understanding of developmental lung stem cell biology and behavior and their potential applications. Lung Stem Cell Behavior is essential reading for researchers in stem cell biology and regenerative medicine, patient advocates, undergraduate students, graduate students, and clinicians interested in cellular therapy and tissue engineering therapies. Front Matter ....Pages i-xxix Brief Overview of the Human Respiratory System Structure and Development (Ahmed El-Hashash)....Pages 1-3 Diversity of Lung Stem and Progenitor Cell Types (Ahmed El-Hashash)....Pages 5-13 Signals and Molecular Mechanisms Controlling Lung Stem/Progenitor Cell Development and Behavior (Ahmed El-Hashash)....Pages 15-25 Signals and Molecular Mechanisms Regulating Stem Cell Behavior in Other Systems (e.g., Hematopoietic Stem Cells) (Ahmed El-Hashash)....Pages 27-34 Mode of Cell Division as a Regulatory Mechanism for Lung Stem Cell Behavior Compared to Other Systems (Ahmed El-Hashash)....Pages 35-55 Lung Stem Cell Plasticity (Ahmed El-Hashash)....Pages 57-59 Lung Stem Cells in Lung Repair and Regeneration (Ahmed El-Hashash)....Pages 61-65 Stem Cell-Based Organoid Models in Lung Development and Diseases (Ahmed El-Hashash)....Pages 67-75 Back Matter ....Pages 77-105