Cell Biology and Translational Medicine, Volume 5: Stem Cells: Translational Science to Therapy

Description

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the fifth volume of a continuing series. Front Matter ....Pages i-xi Therapeutic Cardiac Patches for Repairing the Myocardium (Benjamin W. Streeter, Michael E. Davis)....Pages 1-24 Human Induced Pluripotent Stem Cells in the Curative Treatment of Diabetes and Potential Impediments Ahead (Nidheesh Dadheech, A. M. James Shapiro)....Pages 25-35 CRISPR/Cas9 for Sickle Cell Disease: Applications, Future Possibilities, and Challenges (Selami Demirci, Alexis Leonard, Juan J. Haro-Mora, Naoya Uchida, John F. Tisdale)....Pages 37-52 Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation (David Richards, Joe Swift, Lu Shin Wong, Stephen M. Richardson)....Pages 53-69 Cellular Complexity at the Interface: Challenges in Enthesis Tissue Engineering (Isabel Calejo, Raquel Costa-Almeida, Manuela E. Gomes)....Pages 71-90 Induced Pluripotent Stem Cells in Disease Modelling and Regeneration (Burcu Talug, Zeynep Tokcaer-Keskin)....Pages 91-99 Stem Cells for the Oromaxillofacial Area: Could they be a promising source for regeneration in dentistry? (Ayşegül Mendi, Hacer Ulutürk, Mustafa Sancar Ataç, Derviş Yılmaz)....Pages 101-121 Stem Cells Derived from Dental Tissues (Safa Aydin, Fikrettin Şahin)....Pages 123-132 A Novel Virtue in Stem Cell Research: Exosomes and Their Role in Differentiation (Hüseyin Abdik, Ezgi Avsar Abdik, Ayşen Aslı Hızlı Deniz, Pakize Neslihan Taşlı, Fikrettin Şahin)....Pages 133-146 Mesenchymal Stem Cells as Regulators of Carcinogenesis (Taha Bartu Hayal, Binnur Kıratlı, Hatice Burcu Şişli, Fikrettin Şahin, Ayşegül Doğan)....Pages 147-166 Back Matter ....Pages 167-172