ENGLISH

The TNF Superfamily: Methods and Protocols

By Jagadeesh Bayry (eds.)

Book information

Publisher
Humana Press
Year
2014
ISBN
1493906682, 9781493906680
DOI
10.1007/978-1-4939-0669-7
ISSN
1064-3745
LCC
2014937463
Language
english
Format
PDF
Filesize
5 MB (4891542 bytes)
Series
Methods in Molecular Biology 1155
Edition
1
Pages
226\239
Topic
Biology Molecular
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2014-05-02 09:27:39
Protein Science

Description

Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis.

Similar books