Multi-Pronged Omics Technologies to Understand COVID-19

Description

"COVID-19 and Omics Technologies" is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies. It demonstrates how omics technologies could better investigate the infectious disease and propose solutions to the current concerns. The value of multi-omics technologies in understanding disease etiology and host response, discovering infection biomarkers and illness prediction, identifying vaccine candidates, discovering therapeutic targets, and tracing pathogen evolution is discussed in this book. These factors combine to make it a valuable resource to enhance understanding of both "Omics technology" and "COVID-19" as a disease. The book covers the most recent understanding of COVID-19 and the applications of cutting-edge studies, making it accessible to a large multidisciplinary readership. The book explains how high-throughput technologies and systems biology might assist to solve the pandemic’s challenges and deconstruct and appreciate the substantial contributions that omics technologies have made in predicting the path of this unforeseeable pandemic. Features In-depth summary of clinical presentation, epidemiological impact, and long-term sequelae of COVID-19 pandemic. A systematic overview of omics-based approaches to the study of COVID-19 biology. Recent research results and some pointers to future advancements in methodologies used. Detailed examples from recent studies on COVID-19 encompassing different omics methodologies. A detailed description of methodologies and notes on the applications of state-of-the-art technologies. This book is intended for scientists who need to understand the biology of COVID-19 from the perspective of omics investigations, as well as researchers who want to employ omics-based technologies in disease biology. Cover Half Title Title Copyright Contents Preface Editor biography List of contributors 1 Clinical and epidemiological context of COVID-19 2 NGS technologies for detection of SARS-CoV-2 strains and mutations 3 Mass spectrometry techniques for detection of COVID-19 viral and host proteins using naso-oropharyngeal swab and plasma 4 Targeted proteomic approaches in the context of COVID-19 pandemic 5 Metabolomics: Role in pathobiology and therapeutics of COVID-19 6 Protein microarrays for COVID-19 research: Biomarker discovery, humoral response and vaccine targets 7 COVID-19 pathogenesis and host immune response 8 Putative role of multi-omics technologies in the investigation of persistent effects of COVID-19 on vital human organs 9 Insights into interactomics-driven drug repurposing to combat COVID-19 10 Spectroscopy methods for SARS-CoV-2 detection 11 Role of AI and ML in empowering and solving problems linked to COVID-19 pandemic Index