The Organic Chemistry of Drug Synthesis, vol.4

Description

New york - Chichester - Brisbane – Toronto: A Wiley-Interscience publication, 1990. - 254 p.This book is addressed primarily to practitioners in the field who seek a quick overview of the synthetic routes which have been used to access specific classes of therapeutic agents. Publica-tions of syntheses of such compounds in the open literature remains a sometimes thing. One can, however, be certain that any compound which has commercial potential will be covered by a patent application. Many of the references are thus to the patent literature. Graduate students in medicinal and organic chemistry may find this book useful as an adjunct to the more traditional texts in that it provides many examples of actual applications of the chemistry which is the subject of their study. This volume, like those which came before, presumes a good working knowledge of chemical synthesis and at least nodding acquaintance with biology and pharmacology.Aliphatic and Alicyclic CompoundsMonocyclic Aromatic CompoundsPolycyclic Aromatic Compounds and Thier Reduction ProductsSteroidsFive-Membered Ring HeterocyclesSix- Membered Ring HeterocyclesFive-Membered Ring Benzofused HeterocyclesSix-Membered Ring Benzofused HeterocyclesBicyclic Fused Heterocyclesβ-Lactam AntibioticsMiscellaneous Heterocycles