ENGLISH

Metal Catalyzed Cascade Reactions

By Ei-ichi Negishi , Guangwei Wang , Gangguo Zhu (auth.) , Thomas J. J. Müller (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2006
ISBN
9783540329589, 3-540-32958-7
DOI
10.1007/11603696
ISSN
1436-6002
Open Library ID
OL9056382M
Language
english
Format
DJVU
Filesize
3 MB (3362041 bytes)
Series
Topics in organometallic chemistry 19
Edition
1
Pages
340\294
Time added
2010-04-25 21:59:20
Organometallic Chemistry; Catalysis; Inorganic Che

Description

Transition metal-catalyzed cascade reactions are an elegant approach to complex molecular scaffolds. Besides their esthetics and increase in structural complexity, they have also become mechanistic challenges for the combination of organometallic elementary steps. As a consequence, cascade reactions have revolutionized synthetic strategies and conceptual thinking. The authors highlight cyclization via carbopalladation and acylpalladation and Heck-pericyclic sequences. They discuss p-allyl palladium-based cascade reactions, Michael-type additions as an entry to transition-metal-promoted cyclizative transformations, and sequential or consecutive palladium-catalyzed processes, and show Pauson-Khand cascades, metal-catalyzed cyclizations of acyclic precursors, as well as cascade and sequential ruthenium-catalyzed transformations. Therefore, the reader finds overview of an exciting and highly dynamic field of a new and innovative methodological concept.

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