Palladium in Organic Synthesis: -/-

Description

Palladium is a remarkable metal. In particular, organopalladium chemistry has made remarkable progress over the last 30 years. That progress is still continuing, without any end in sight. This book presents a number of accounts and reviews on the novel Pd-catalyzed reactions discovered mainly in the last five years. The book covers Pd-catalyzed reactions that are new – entirely different from the more standard ones. Topics such as new reactions involving ß-carbon elimination and formation of palladacycles as key reactions, cross-coupling of unactivated alkyl electrophiles with organometallic compounds, arylation via C-H bond cleavage, Pd/norbornene-catalyzed aromatic functionalizations, three-component cyclizations of allenes, use of N-heterocyclic carbenes as ligands, asymmetric reactions catalyzed by Pd(II) compounds such as Lewis acids, cycloadditions of arynes and alkynes, and nucleophilic attack by Pd species are surveyed in detail by researchers who have made important contributions to these fields. The book addresses graduate students majoring in organic synthesis and researchers in academic and industrial institutes. Catalytic Processes Involving β-Carbon Elimination....Pages 1-20 Novel Methods of Aromatic Functionalization Using Palladium and Norbornene as a Unique Catalytic System....Pages 21-53 Arylation Reactions via C-H Bond Cleavage....Pages 55-83 Palladium-Catalyzed Cross-Coupling Reactions of Unactivated Alkyl Electrophiles with Organometallic Compounds....Pages 85-108 Palladium-Catalyzed Cycloaddition Reactions of Arynes....Pages 109-146 Palladium-Catalyzed Annulation of Alkynes....Pages 147-182 Palladium-Catalyzed Two- or Three-Component Cyclization of Functionalized Allenes....Pages 183-210 Nucleophilic Attack by Palladium Species....Pages 211-239 The Use of N -Heterocyclic Carbenes as Ligands in Palladium-Mediated Catalysis....Pages 241-278 Active Pd(II) Complexes as Either Lewis Acid Catalysts or Transition Metal Catalysts....Pages 279-321