ENGLISH

RNA Interference: Challenges and Therapeutic Opportunities

By Mouldy Sioud (eds.)

Book information

Publisher
Humana Press
Year
2015
ISBN
1493915371, 9781493915378
DOI
10.1007/978-1-4939-1538-5
ISSN
1064-3745
LCC
2014949774
Language
english
Format
PDF
Filesize
15 MB (15927531 bytes)
Series
Methods in Molecular Biology 1218
Edition
1
Pages
495\513
Topic
Biology Genetics
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2014-10-19 19:55:55
Pharmacology/Toxicology; Human Genetics

Description

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies.

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