ENGLISH

RNA Interference: Challenges and Therapeutic Opportunities

By Mouldy Sioud (eds.)

Book information

Publisher
Humana Press
Year
2015
ISBN
978-1-4939-1537-8, 978-1-4939-1538-5
DOI
10.1007/978-1-4939-1538-5
Language
english
Format
PDF
Filesize
17 MB (17492961 bytes)
Series
Methods in Molecular Biology 1218
Edition
1
Pages
495\496
Time added
2014-11-10 20:00:00
Pharmacology/Toxicology; Human Genetics

Description

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies.

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