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Current Topics in Cellular Regulation, Volume 6 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation. Organized into eight chapters, this volume begins with an overview of the well-defined stages of sporulation that can be correlated with the appearance of several enzymes, ultrastructures, and chemical components associated with the developing spore. This text then examines the regulatory properties of G6PD from various sources, with emphasis to those cells in which these properties may operate in vivo in the control of carbohydrate metabolism. Other chapters consider the various methods for analyzing biochemical systems. The final chapter deals with kinetic cooperativity, which is the basis of the flip-flop mechanism. This book is a valuable resource for biochemists, biologists, and research workers. Content: Contributors to Volume 6Page ii Front MatterPage iii Copyright pagePage iv List of ContributorsPage ix PrefacePage xiBERNARD L. HORECKER, EARL R. STADTMAN Preface to Volume 6Page xiiBERNARD L. HORECKER, EARL R. STADTMAN Contents of Previous VolumesPages xiii-xvii Role of Proteases in SporulationPages 1-20ROY H. DOI Regulatory Properties of Glucose-6-Phosphate DehydrogenasePages 21-62A. BONSIGNORE, A. DE FLORA The Behavior of Intact Biochemical Control Systems*Pages 63-130MICHAEL A. SAVAGEAU A Possible Role for Kinetic Reaction Mechanism Dependent Substrate and Product Effects in Enzyme RegulationPages 131-167DANIEL L. PURICH, HERBERT J. FROMM Control of Biogenesis of Isoprenoid Compounds in AnimalsPages 169-207T. RAMASARMA On Allosteric ModelsPages 209-226JEFFRIES WYMAN Regulation of Uridylic Acid Biosynthesis in Eukaryotic CellsPages 227-265MARY ELLEN JONES Flip-Flop Mechanisms and Half-Site EnzymesPages 267-310MICHEL LAZDUNSKI AUTHOR INDEXPages 311-329 SUBJECT INDEXPages 330-334