Allogeneic Stem Cell Transplantation

Description

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation. Front Matter....Pages i-xix Allogeneic Stem Cell Transplantation: The Last Century....Pages 1-9 Full Intensity and Reduced Intensity Allogeneic Transplantation in AML....Pages 11-27 Allogeneic Stem Cell Transplantation for Adult Acute Lymphoblastic Leukemia (ALL)....Pages 29-42 Hematopoietic Progenitor Cell Transplantation for Treatment of Chronic Lymphocytic Leukemia....Pages 43-52 The Role of Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelogenous Leukemia Patients in the Era of Tyrosine Kinase Inhibitors....Pages 53-74 Allogeneic Transplantation for Hodgkin’s Lymphoma....Pages 75-88 Myeloablative Allogeneic Stem Cell Transplantation for Non-Hodgkin’s Lymphoma....Pages 89-108 Non-Hodgkin’s Lymphoma: Allogeneic Reduced Intensity Conditioning....Pages 109-125 The Role of Allogeneic Transplantation for Multiple Myeloma in Older Adults....Pages 127-142 Single Versus Tandem Autologous Hematopoietic Stem Cell Transplant in Multiple Myeloma....Pages 143-157 Treatment Strategies for Follicular Center Cell Non-Hodgkin’s Lymphoma....Pages 159-175 The Role of Transplantation in Favorable-Risk Acute Myeloid Leukemia....Pages 177-192 Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukaemia in Adults....Pages 193-202 Allogeneic Transplantation for Myelodysplastic Syndromes....Pages 203-217 Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia....Pages 219-260 Allogeneic Transplantation for the Treatment of Multiple Myeloma....Pages 261-279 Blood Vs. Marrow Allogeneic Stem Cell Transplantation....Pages 281-297 Hematopoietic Cell Transplantation from Partially HLA-Mismatched (HLA-Haploidentical) Related Donors....Pages 299-343 Unrelated Donor Transplants....Pages 345-361 Update on Umbilical Cord Blood Transplantation....Pages 363-374 Selection of Cord Blood Unit(s) for Transplantation....Pages 375-386 Mobilization of Hematopoietic Cells Prior to Autologous or Allogeneic Transplantation....Pages 387-412 Natural Killer-Cell Based Treatment in Hematopoetic Stem Cell Transplantation....Pages 413-425 Cryopreservation of Allogeneic Stem Cell Products....Pages 427-439 Concepts and Controversies in the Use of Novel Preparative Regimens for Allogeneic Stem Cell Transplantation....Pages 441-458 Allogeneic Haematopoietic Stem Cell Transplantation and Natural Killer Cell Alloreactivity....Pages 459-476 Therapeutic Potential of Mesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation....Pages 477-490 Hematopoietic Stem Cell Transplantation for Thalassemia....Pages 491-504 Viral Infections in Hematopoietic Stem Cell Transplant Recipients....Pages 505-532 Fungal Infections....Pages 533-544 Immune Reconstitution and Implications for Immunotherapy Following Hematopoeitic Stem Cell Transplantation....Pages 545-564 Acute Graft Versus Host Disease: Prophylaxis....Pages 565-576 Chronic Graft-Versus-Host Disease....Pages 577-595 Post-transplant Lymphoproliferative Disorder....Pages 597-618 Psychological Care of Adult Allogeneic Transplant Patients....Pages 619-656 Second Allogeneic Transplantation: Outcomes and Indications....Pages 657-666 Minimal Residual Disease....Pages 667-685 Functional Assessment Tools and Co-morbidity Scoring in Hematopoietic Progenitor Cell Transplantation....Pages 687-694 Unique Thrombotic and Hemostatic Complications Associated with Allogeneic Hematopoietic Stem Cell Transplantation....Pages 695-715 How Much Isolation Is Enough for Allografts?....Pages 717-732 Monoclonal Antibodies in Allogeneic Hematopoietic Stem Cell Transplantation for Hematologic Malignancies....Pages 733-746 Treatment of Acute Graft-vs-Host Disease....Pages 747-765 The Importance of Non-Human Primate Models for Pre-clinical Studies in Hematopoiesis....Pages 767-787 In Vivo Models of Allogeneic Hematopoietic Stem Cell Transplantation....Pages 789-805 Dendritic Cells....Pages 807-854 Augmentation of Hematopoietic Stem Cell Transplantation with Anti-cancer Vaccines....Pages 855-867 Erratum To....Pages 869-870 Back Matter....Pages 871-883