Best Practices in Processing and Storage for Hematopoietic Cell Transplantation

Description

This concise book examines clinically relevant issues relating to the ways in which bone marrow, cord blood and apheresis products, are processed and stored for the purpose of Hematopoietic Cell Transplantation and Cell Therapy. The twin aims are to offer up-to-date content covering a wide spectrum of topics and controversies and to provide practitioners in the field of transplant and cell therapy with practical, immediately applicable information from the internationally experts in the field. Each chapter focuses on a particular subject, and numerous working tables, algorithms, and figures are included. Whenever appropriate, the reader’s attention is drawn to the availability of potentially high-impact clinical trials and expert practices. The authors are all experts who have been carefully selected for their knowledge of the topics that they address. The book will appeal to clinical and laboratory personnels, residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant products and patients. Its format ensures that it will also serve as a robust, engaging tool to aid vital activities in every hematology and oncology trainee’s daily work. Front Matter ....Pages i-vi Journey of Hematopoietic Cells: Processing to Infusion (Beth Shaz, Joseph Schwartz)....Pages 1-4 Regulations and Accreditation of Processing Laboratories (Yvette C. Tanhehco, Joseph Schwartz)....Pages 5-20 Front Matter ....Pages 21-21 Donor Qualification for Hematopoietic Cell Transplantation (Patricia Shi)....Pages 23-35 Routine Hematopoietic Progenitor Cell Processing: HPC, Apheresis and HPC, Marrow Products (Jay S. Raval, Kathryn McKay, Yara A. Park)....Pages 37-50 CD34+ Enrichment and T-Cell Depletion (Scott T. Avecilla, Cheryl A. Goss)....Pages 51-62 Cryopreservation Techniques and Freezing Solutions (Rona Singer Weinberg)....Pages 63-72 Peripheral Blood Hematopoietic Progenitor Cell Graft Thawing (Ronit Reich-Slotky)....Pages 73-83 Front Matter ....Pages 85-85 Cord Blood Donor Qualification (Ngaire J. Elwood)....Pages 87-96 Cord Blood Processing: Different Bags and Automation (Ludy Dobrila)....Pages 97-112 Cord Blood Graft Assessment and Selection Criteria for Transplantation (Andromachi Scaradavou)....Pages 113-136 Cord Blood Graft Thawing (Ronit Reich-Slotky)....Pages 137-148 Hematopoietic Graft Handling During Transportation (David Ming-Hung Lin, Jeannene Marie Gibbons, Alexander Thomas Gallacher, Rebecca Haley)....Pages 149-160