ENGLISH

Heterologous Expression of Membrane Proteins: Methods and Protocols

Book information

Publisher
Humana Press
Year
2016
ISBN
1493936352, 9781493936359
DOI
10.1007/978-1-4939-3637-3
ISSN
1064-3745
LCC
2016935861
Language
english
Format
PDF
Filesize
11 MB (11270448 bytes)
Series
Methods in Molecular Biology 1432
Edition
2nd ed. 2016
Pages
xii+322\335
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2016-08-11 06:56:57

Description

This detailed volume encompasses chapters from leading experts in the area of membrane proteins who describe step-by-step protocols developed these last few years to improve the functional production and stabilization of recombinant integral membrane proteins (IMPs). Membrane proteins play a key role in numerous pathologies such as cancer, cystic fibrosis, epilepsy, hyperinsulinism, and Alzheimer’s disease, yet studies on these and other disorders are hampered by a lack of information about the proteins involved. This book sets out to aid researchers in rectifying this situation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Heterologous Expression of Membrane Proteins: Methods and Protocols, Second Edition serves as an ideal guide for scientists attempting to delve deeper into the myriad unique IMP structures.

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