Complex Sleep Breathing Disorders. A Clinical Casebook of Challenging Patients

Description

© Preface Contents Contributors Chapter 1: Hypercapnic Obstructive Sleep Apnea Case Discussion Respiratory Chemoreflexes and Disease Trait Versus State Components of the Respiratory Chemoreflex The Importance of Hypocapnia and the CO2 Reserve in Central Sleep Apnea and Periodic Breathing Polysomnographic Recognition of High Loop Gain Sleep Apnea Carbonic Anhydrase Inhibition Oxygen as Adjunctive Therapy for Hypercapnic Periodic Breathing Adaptive Ventilation for Hypercapnic Periodic Breathing References Chapter 2: Central Sleep Apnea and Opioid Use Case Discussion Introduction Diagnosis Epidemiology and Risk Factors Pathogenesis Consequences Treatment Complex Sleep Apnea Due to Opioids References Chapter 3: Sleep Apnea and Stroke Case Presentation Discussion Pathogenesis Assessment and Diagnosis Treatment of Sleep-Disordered Breathing References Chapter 4: Obstructive and Central Sleep Apnea Treatment Challenges in Atrial Fibrillation Case History and Examination Evaluation Diagnosis Outcome Discussion Introduction Epidemiology and Clinic-Based Studies Characterizing the Relationship of Sleep Apnea and Atrial Fibrillation Sleep Apnea and Atrial Fibrillation Pathophysiology Treatment of Obstructive Sleep Apnea in Atrial Fibrillation Treatment of Central Sleep Apnea/Cheyne-Stokes Breathing in Atrial Fibrillation References Chapter 5: Cheyne-Stokes Breathing and Diastolic Heart Failure Case Baseline Night CPAP Titration Night ASV Control Nights Chronic Follow-Up with ASV Discussion References Chapter 6: Pulmonary Hypertension in Obstructive Sleep Apnea Introduction Case Report Discussion Mechanism of PH in OSA Diagnostic Considerations Effect of Treatment of OSA on PH References Chapter 7: Primary Central Sleep Apnea Case Discussion Definition Epidemiology and Demographics Pathophysiology of Primary Central Sleep Apnea Clinical Signs and Symptoms Treatment References Chapter 8: Treatment-Emergent Central Sleep Apnea Case Discussion Section Introduction Pathophysiology Diagnosis, Epidemiology, and Natural History Clinical Presentation and Evaluation History Associated Conditions Polysomnographic Features Home Sleep Apnea Testing (HSAT) and PAP Data Assessments of Physiologic Contributors to TE-CSA Treatment Conservative Measures PAP Therapies Non-PAP Therapies References Chapter 9: Upper Airway Resistance Syndrome Case Discussion Introduction Epidemiology Clinical Presentation Polysomnographic Findings Pathophysiology Treatment Conclusion References Chapter 10: Sleep Apnea in Pregnancy Case Discussion Normal Respiratory Physiology Changes During Pregnancy Sleep-Disordered Breathing in Pregnancy Diagnosis of SDB in Pregnancy Sleep Apnea in Pregnancy Affects the Health of Mother and Infant Treating Sleep Disordered Breathing in Pregnancy References Chapter 11: Obesity Hypoventilation Syndrome Case Discussion Epidemiology Definition Pathophysiology Diagnosis Management References Chapter 12: Sleep Breathing Disorders in Amyotrophic Lateral Sclerosis Case Discussion References Chapter 13: Alveolar Hypoventilation and Non-invasive Ventilation in COPD Case Presentation Assessment Management Outcome Discussion References Chapter 14: Hypoventilation Associated with Scoliosis Case Discussion Introduction Epidemiology Clinical Presentation Polysomnographic Findings Pathophysiology Treatment Conclusion References Chapter 15: Postoperative Respiratory Failure Case Scenario Discussion Mechanisms of Postoperative Respiratory Failure Predicting Postoperative Respiratory Failure Obstructive Sleep Apnea and Postoperative Respiratory Failure Perioperative Management to Mitigate Postoperative Respiratory Failure Intraoperative Ventilation Management to Prevent Postoperative Respiratory Failure Residual Neuromuscular Blockade Postoperative Management and Rescue Modalities Conclusion References Chapter 16: Sleep Disordered Breathing at High Altitude Clinical Presentation Discussion References Chapter 17: Congenital Central Hypoventilation Syndrome (CCHS) Case Discussion Diagnostics Phenotype Treatment and Surveillance References Chapter 18: Sleep Disordered Breathing and Prader-Willi Syndrome Case Presentation Discussion Ventilatory Control Obstructive Sleep Apnea Growth Hormone Central Sleep Apnea Sleep-Related Hypoventilation Hypersomnia References Chapter 19: Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) Case Presentation Discussion History of ROHHAD Etiology Presentation Differential Diagnosis Management References Chapter 20: Chiari Malformations Case Discussion References Chapter 21: Sleep Breathing Disorders in Duchenne Muscular Dystrophy Case Discussion References Index