Practical Breast Pathology: Frequently Asked Questions
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Description
This comprehensive volume reviews current topics and controversies in diagnostic breast pathology, and addresses frequently encountered diagnostic problems using a question and answer format and case presentations. Emphasis is placed on the diagnostic approach as it relates to morphology, clinical and radiographic correlation, differential diagnosis, and ancillary testing including immunohistochemical and molecular analyses. Answers are provided and serve as a practical, evidence-based, and problem solving guide to diagnostic issues having significant impacts on clinical management. Common but diagnostically challenging entities such as papillary lesions and fibroepithelial lesions are discussed in detail, as well as special types of breast cancer including solid papillary carcinoma, lobular lesions and its variants. Uncommon breast lesions such as mesenchymal, lymphoid, and metastatic lesions are also covered. Chapters discuss genetic alterations and molecular abnormalities in breast cancer, and commonly encountered interpretation dilemmas on immunohistochemistry in breast cancer and metastatic cancer to the breast with a focus on prognostic and predictive tumor biomarkers. Front Matter ....Pages i-xiv Intraductal Proliferative Disease of the Breast (Xiuzhen Duan, Yihong Wang, Hua Guo, Ping Tang)....Pages 1-24 Invasive Ductal Carcinoma (NOS) of the Breast (Xiaoxian Li, Zaibo Li, Xiaoyan Cui, Yan Peng)....Pages 25-37 Invasive Carcinoma of the Breast: Special Types (Zaibo Li, Xiaoyan Cui, Xiaoxian Li, Yan Peng)....Pages 39-71 Lobular Breast Lesions (Megan L. Troxell, Yun An Chen, Jing Yu, Debra M. Ikeda, Kimberly H. Allison)....Pages 73-143 Papillary Lesions of the Breast (IDP, IDPC, EPC, SPC) (Julia Y. Tsang, Ping Tang, Gary M. Tse)....Pages 145-157 Fibroepithelial Lesions (Phyllodes Tumor and Fibroadenoma) of the Breast (Julia Y. Tsang, Gary M. Tse)....Pages 159-171 Immunohistochemistry in Breast Cancer (Ping Tang, Marilyn M. Bui, Yan Peng)....Pages 173-192 Breast Cancer with Hereditary Cancer Predisposition Syndromes (Roshni Rao, Caitlin B. Mauer, Margaret Chen-Seetoo, Yan Peng)....Pages 193-201 Mesenchymal and Lymphoid Lesions in the Breast (Xi Wang, Andrew G. Evans)....Pages 203-236 Metastatic Cancer in the Breast (Bradley M. Turner)....Pages 237-257 Back Matter ....Pages 259-265
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