Pheochromocytomas, Paragangliomas and Disorders of the Sympathoadrenal System

Description

Providing a comprehensive review of the most up-to-date evidence, this book presents the latest biology, diagnosis and management for pheochromocytomas, paragangliomas and related disorders of the sympathoadrenal system. Many new areas, including genetic syndromes, have evolved, and these are insufficiently appreciated among practitioners. A discussion of the basics of catecholamine biology sets the stage for presentations of the pathology, clinical features, and diagnosis of these tumors, including localization and imaging. Medical, anesthetic and surgical management of pheochromocytomas and paragangliomas follow, including case material. Additional chapters discuss pheochromocytoma in pediatrics and in pregnancy, both pure and hypoglycemia-associated autonomic failure, and the role of the sympathetic nervous system in hypertension. These diseases are relatively rare, but many, if not most, go undiagnosed during life: If promptly diagnosed and appropriately treated, they are usually completely curable; if undiagnosed or mistreated, they are typically terminal. Bringing the most current knowledge to bear, Pheochromocytomas, Paragangliomas and Disorders of the Sympathoadrenal System will be a valuable resource for practicing endocrinologists, endocrine surgeons, internists and endocrine fellows faced with diagnosing and managing these conditions. Front Matter ....Pages i-xii Catecholamines (Lewis Landsberg)....Pages 1-14 Pathology of Pheochromocytoma and Paraganglioma (John Turchini, Anthony J. Gill, Arthur S. Tischler)....Pages 15-37 Clinical Features of Pheochromocytoma and Paraganglioma (Lewis Landsberg)....Pages 39-61 Heritable and Syndromic Pheochromocytoma and Paraganglioma (Peter Kopp)....Pages 63-87 Pheochromocytoma and Paraganglioma in the Pediatric Population (Rachel Kadakia, Monica Bianco, Elizabeth Dabrowski, Donald Zimmerman)....Pages 89-97 Diagnosis of Pheochromocytoma and Paraganglioma (William F. Young)....Pages 99-111 Localization of Pheochromocytoma and Paraganglioma (Carla B. Harmath, Hatice Savas)....Pages 113-126 Medical Management of Pheochromocytoma (Daniel J. Toft, Mark E. Molitch)....Pages 127-141 Anesthetic Management of Pheochromocytoma and Paraganglioma (Ljuba Stojiljkovic)....Pages 143-156 Surgery for Pheochromocytoma (Benjamin Deschner, Dina Elaraj)....Pages 157-166 Pheochromocytoma in Pregnancy (Kenneth K. Chen)....Pages 167-172 Pure Autonomic Failure: Diagnosis, Differential Diagnosis, and Natural History (Pearl K. Jones, Roy Freeman)....Pages 173-182 Hypoglycemia-Associated Autonomic Failure in Diabetes (Philip E. Cryer, Ana Maria Arbelaez)....Pages 183-199 The Sympathetic Nervous System in Hypertension (Gino Seravalle, Giuseppe Mancia, Guido Grassi)....Pages 201-212 Back Matter ....Pages 213-220