Paper-based Diagnostics: Current Status and Future Applications

Description

This book explores the status of paper-based diagnostic solutions, or Microfluidics 2.0. The contributors explore: how paper-based tests can be widely distributed and utilized by semi-skilled personnel; how close to commercial applications the technology has become, and what is still required to make paper-based diagnostics the game-changer it can be. The technology is examined through the lens of the World Health Organization’s ASSURED criteria for low-resource countries (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free, and Deliverable to end-users). Its applications have to include: health technology, environmental technology, food safety, and more. This book is appropriate for researchers in these areas, as well as those interested in microfluidics, and includes chapters dedicated to principles such as theory of flow and surface treatments; components such as biomarkers and detection; and current methods of manufacturing. Discusses how paper-based diagnostics can be used in developing countries by comparing current diagnostic tests with the World Health Organization's ASSURED criteria Examines how paper-based diagnostics could be integrated with other technologies, such as printed electronics, and the Internet of Things. Outlines how semi-skilled personnel across a variety of fields can implement paper-based diagnostics Front Matter ....Pages i-ix Unmet Diagnostics Needs for the Developing World (Kevin J. Land, Suzanne Smith, Rosanna W. Peeling)....Pages 1-21 The Role of Paper Chemistry and Paper Manufacture in the Design of Paper-Based Diagnostics (Samuel Schabel, Markus Biesalski)....Pages 23-46 Critical Components and Innovations in Paper-Based Analytical Devices (Robert B. Channon, Monpichar Srisa-Art, Katherine Boehle, Charles Henry)....Pages 47-87 How Are These Devices Manufactured? (Giorgio Gianini Morbioli, Thiago Mazzu-Nascimento, Amanda M. Stockton, Emanuel Carrilho)....Pages 89-122 Printed Functionalities on Paper Substrates Towards Fulfilment of the ASSURED Criteria (Suzanne Smith, Dario Mager, Jan G. Korvink, Kevin J. Land)....Pages 123-170 The Many Roads to an Ideal Paper-based Device (Margot Karlikow, Keith Pardee)....Pages 171-201 The Fascination of Paper (Jan G. Korvink)....Pages 203-214 Back Matter ....Pages 215-220