Inhalation aerosols : physical and biological basis for therapy

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0. IntroductionAnthony J. Hickey and Heidi M. MansourSection 1 FundamentalsPhysicochemical Properties of Respiratory Particles and FormulationsB. ShekunovParticle Deposition in the Respiratory Tract and the Effect of Respiratory DiseaseDr. William BennettMathematical Modeling of Inhaled Therapeutic Aerosol Deposition in the Respiratory TractJeffry Schroeter, Bahman Asgharian, and Julia KimbellLung transporters & absorption mechanisms in the lungs. Mohammed Ali Selo,, Hassan H. A. Al-Alak, Carsten EhrhardtBioavailability of inhaled compounds. L. Garcia-Contreras3D models as tools for inhaled drug development. Sally-Ann Cryan, Jennifer Lorigan, Cian O'LearyOverview of the delivery technologies for inhalation aerosols Daniel F. Moraga-Espinoza, Ashlee D. Brunaugh, Silvia Ferrati, Lara A. Heersema, Matthew J. Herpin, Patricia P. Martins, Hairui Zhang, Hugh D. C. Smyth Section 2 Applications, Influence of Lung Disease Pathophysiology on Aerosol Deposition, Inhaler Device Technique in Respiratory Disease, & Clinical Outcomes in Drug Performance Assessment Neonatal & Pediatric Inhalation Drug DeliveryAriel Berlinski AsthmaOmar UsmaniDrug Delivery in Pulmonary AspergillosisSawittree Sahakijpijarn, Jay I. Peters, Robert O. Williams IIILung Cancer Inhalation TherapeuticsRajiv DhandInhaled Therapeutics in Chronic Obstructive Pulmonary DiseaseTejas Sinha, Paul DeJulio and Philip Diaz Cystic fibrosis infection & Biofilm BustersJennifer Fiegel and Sachin GharseCURRENT AND FUTURE CFTR Therapeutics-Marne C. Hagemeijer, Gimano D. Amatngalim and Jeffrey M. Beekman Innate and Adaptive Barrier Properties of Airway MucusAlison Schaefer, Samuel K. LaiNon-tuberculous mycobacteria (NTM)M. Ghadiri, P. M. Young, and D. TrainiInhalational Therapies for Non-CF Bronchiectasis Ashvini Damodaran, Dustin R. Fraidenburg, and Israel RubinsteinPulmonary Fibrosis, Priya Muralidharan, Dr. Don Hayes, Jr, and Dr. Heidi M. MansourTherapeutics in Pulmonary HypertensionMaria F. Acosta, Don Hayes, Jr., Jeffrey R. Fineman, Jason X.-J. Yuan, Stephen M. Black, and Heidi M. MansourRespiratory distress syndrome, Heidi M. Mansour, Debra Droopad, and Julie G. LedfordSurfactant Aerosol Therapy for nRDS and ARDSDonovan B. YeatesFundamentals in Nasal Drug Delivery Zachary Warnken, Yu jin Kim, Heidi M. Mansour, Robert O. Williams III, Hugh D.C. SmythInhaled therapeutics against TB: the promise of pulmonary treatment and prevention strategies in the clinicDominique N Kunda, Nitesh K. Miller, Elliott K. Muttil, PavanSection 3 Integrated strategies (reflecting combined elements from chapters 8-23): Inhaled medication: factors that affect lung depositionJoy ConwayA Critical Perspective on Future developments based on the knowledge we have nowTania F. Bahamondez-Canas, Jasmim Leal, Hugh D.C. Smyth 26. Ensuring Effectiveness and Reproducibility of Inhaled Drug Treatment Anthony J Hickey27. ConclusionA.J. Hickey, and H.M. Mansour