ENGLISH

Growth Hormone Secretagogues: Basic Findings and Clinical Implications

By E. Ghigo , M. Boghen , F.F. Casanueva , C. Dieguez

Book information

Publisher
Elsevier Science
Year
1999
ISBN
0444829334, 9780444829337
Open Library ID
OL18137489M
Language
english
Format
PDF
Filesize
21 MB (22058402 bytes)
Edition
1st
Pages
319\319
Scanned
yes
Time added
2011-08-31 04:54:40

Description

Growth hormone secretagogues (GHS) administered alone or in combination with growth hormone releasing hexapeptides, are effective probes for the diagnosis of GH deficiency in both children and adults. Current research has developed and tested different GHS compounds that are active by the oral route, and have improved potency and bioavailability, giving rise to exciting therapeutic possibilities. There was an enthusiastic response from experts in this area to the idea of distilling the huge amount of available data into one multi-authored volume. Each contributor has advanced the field of knowledge, and has here emphasized the practical aspects of their work, reviewing the subject in the light of their own experience. Therefore, the theme of the book is a practical one. The volume deals with all aspects of GHS that are relevant to the field, from the chemical structure to the different analogues, to the cloning and expression of the GHS-receptor and the role of these compounds in the physiological control of GH secretion. Also discussed are the most recent advances in relation to the possible role of these compounds in the diagnostic therapeutic settings in different clinical situations, either in children, adults or the elderly. The book meets the requirement of covering most, if not all of the advances in the field. It will enable scientists and clinicians to keep abreast of the rapidly evolving knowledge of the most recent years, and will also prove useful as a review for all interested in this topic.

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